Technetium (99mTc) sestamibiDISPLAYTITLE:Technetium (99mTc) sestamibi Technetium (99mTc) sestamibi (INN) (commonly sestamibi; USP: technetium Tc 99m sestamibi; trade name Cardiolite) is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six (sesta=6) methoxyisobutylisonitrile (MIBI) ligands. The anion is not defined. The generic drug became available late September 2008. A scan of a patient using MIBI is commonly known as a "MIBI scan".
Supercritical water reactorThe supercritical water reactor (SCWR) is a concept Generation IV reactor, designed as a light water reactor (LWR) that operates at supercritical pressure (i.e. greater than 22.1 MPa). The term critical in this context refers to the critical point of water, and must not be confused with the concept of criticality of the nuclear reactor. The water heated in the reactor core becomes a supercritical fluid above the critical temperature of 374 °C, transitioning from a fluid more resembling liquid water to a fluid more resembling saturated steam (which can be used in a steam turbine), without going through the distinct phase transition of boiling.
NeutronThe neutron is a subatomic particle, symbol _Neutron or _Neutron0, which has a neutral (not positive or negative) charge, and a mass slightly greater than that of a proton. Protons and neutrons constitute the nuclei of atoms. Since protons and neutrons behave similarly within the nucleus, and each has a mass of approximately one dalton, they are both referred to as nucleons. Their properties and interactions are described by nuclear physics. Protons and neutrons are not elementary particles; each is composed of three quarks.
Nuclear medicineNuclear medicine or nucleology is a medical specialty involving the application of radioactive substances in the diagnosis and treatment of disease. Nuclear imaging, in a sense, is "radiology done inside out" because it records radiation emitting from within the body rather than radiation that is generated by external sources like X-rays. In addition, nuclear medicine scans differ from radiology, as the emphasis is not on imaging anatomy, but on the function. For such reason, it is called a physiological imaging modality.
Molecular imagingMolecular imaging is a field of medical imaging that focuses on imaging molecules of medical interest within living patients. This is in contrast to conventional methods for obtaining molecular information from preserved tissue samples, such as histology. Molecules of interest may be either ones produced naturally by the body, or synthetic molecules produced in a laboratory and injected into a patient by a doctor. The most common example of molecular imaging used clinically today is to inject a contrast agent (e.
FluidizationFluidization (or fluidisation) is a process similar to liquefaction whereby a granular material is converted from a static solid-like state to a dynamic fluid-like state. This process occurs when a fluid (liquid or gas) is passed up through the granular material. When a gas flow is introduced through the bottom of a bed of solid particles, it will move upwards through the bed via the empty spaces between the particles. At low gas velocities, aerodynamic drag on each particle is also low, and thus the bed remains in a fixed state.
LiquidA liquid is a nearly incompressible fluid that conforms to the shape of its container but retains a nearly constant volume independent of pressure. It is one of the four fundamental states of matter (the others being solid, gas, and plasma), and is the only state with a definite volume but no fixed shape. The density of a liquid is usually close to that of a solid, and much higher than that of a gas. Therefore, liquid and solid are both termed condensed matter.
Neutron cross sectionIn nuclear physics, the concept of a neutron cross section is used to express the likelihood of interaction between an incident neutron and a target nucleus. The neutron cross section σ can be defined as the area in cm2 for which the number of neutron-nuclei reactions taking place is equal to the product of the number of incident neutrons that would pass through the area and the number of target nuclei. In conjunction with the neutron flux, it enables the calculation of the reaction rate, for example to derive the thermal power of a nuclear power plant.
TechnetiumTechnetium is a chemical element with the symbol Tc and atomic number 43. It is the lightest element whose isotopes are all radioactive. All available technetium is produced as a synthetic element. Naturally occurring technetium is a spontaneous fission product in uranium ore and thorium ore, the most common source, or the product of neutron capture in molybdenum ores. This silvery gray, crystalline transition metal lies between manganese and rhenium in group 7 of the periodic table, and its chemical properties are intermediate between those of both adjacent elements.
Neutron captureNeutron capture is a nuclear reaction in which an atomic nucleus and one or more neutrons collide and merge to form a heavier nucleus. Since neutrons have no electric charge, they can enter a nucleus more easily than positively charged protons, which are repelled electrostatically. Neutron capture plays a significant role in the cosmic nucleosynthesis of heavy elements. In stars it can proceed in two ways: as a rapid process (r-process) or a slow process (s-process). Nuclei of masses greater than 56 cannot be formed by thermonuclear reactions (i.
