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Protein-polymer conjugates are widely used in biotechnology and medicine, and non-toxic polymers for bioconjugation would be advantageous for these applications. Herein, we reported the toxicity of polymers synthesized by two commonly employed controlled r ...
Proteins play an essential role in all biological processes and have been attracting more and more attention as drug candidates due to their high specificity and activity. However, their use as therapeutics has been seriously held back given that their abi ...
Aliphatic polyesters receive increasing attention over the last years driven by their application as biodegradable substitutes for conventional commodity thermoplastics and applications in the biomedical field, where amongst the family of biodegradable pol ...
Virus filtration by size exclusion is a robust means of eliminating viruses in blood or pharma products. Porous polymer membranes with a narrow size distribution are used to allow passage of the protein product but retain viruses. The chosen polymer must r ...
The development of innovative bioanalytical technologies that enable the discovery of new therapeutics or the creation of systems for rapid, accurate and parallel analyses has gained an extraordinary interest in the biomedical sector in the last 10-15 year ...
In blends of unsaturated polyester (UP), poly (vinyl acetate) (PVAc), and styrene, a reaction-induced phase separation occurs upon curing that is due to the crosslinking between styrene and the UP molecules. The evolution of the morphology was observed by ...
The term polymer brush refers to a well defined arrangement of polymer chains, which are tethered with one end to an interface and usually the surface of a solid substrate. Due to steric repulsion the polymer chains furthermore adopt a defined, stretched c ...
Expts. of Me methacrylate dispersion polymn. are carried out in a reaction calorimeter using PDMS-mMA (methacrylate-terminated polydimethylsiloxane) as surfactant. Different stabilizer concns. from 0 to 10 wt% with respect to monomer have been considered i ...
The rigidity temperature of a solidifying alloy is the temperature at which the solid plus liquid phases are sufficiently coalesced to transmit long range tensile strains and stresses. It determines the point at which thermally induced deformations start t ...
DIGE (difference in gel electrophoresis) proteomics is exploited here to gain insight into the molecular mechanisms of two established ruthenium-based antimetastatic agents, namely trans-[tetrachloro (DMSO) (imidazole)ruthenate(III)] (NAMI-A) and [Ru(eta(6 ...
