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Mycobacterium lepromatosis is an uncultured human pathogen associated with diffuse lepromatous leprosy and a reactional state known as Lucio's phenomenon. By using deep sequencing with and without DNA enrichment, we obtained the near-complete genome sequen ...
Proteins are a ubiquitous and indispensable element for every living organism, from simple bacteria to mammals. Already in the simplest organisms, there exist some thousands of different protein species that take up a great variety of structures, and thus ...
Environmental heterogeneity is one of the main actors of biodiversity and species adaptation as it exerts a selective pressure on observable characteristics of living organisms. Consequently, local adaptation favours certain genetic variants and, by doing ...
The Golgi phosphoprotein 3 (GOLPH3) is encoded by a gene that is located in a region of the human genome that is often amplified in different solid tumours. GOLPH3, an evolutionary conserved phosphatidylinositol 4-phosphate (PI4P) binding protein, is mainl ...
This dissertation describes a set of research projects that were conducted between 2012 and 2014 in order to answer the question how do computational ideas alter our understanding of place? Each project was produced in the context of the performing arts an ...
Background: New experimental methods must be developed to study interaction networks in systems biology. To reduce biological noise, individual subjects, such as single cells, should be analyzed using high throughput approaches. The measurement of several ...
DRAMA framework was primarily developed with the purpose of facilitating data integration into genome scale models (GEM) of cellular metabolism. The existence of differently annotated genome scale models and metabolomics datasets that are provided without ...
Supervisory Control and Data Acquisition (SCADA) systems are nowadays widely used in modern industry. Their utility has been proven over the past decades to supervise any automated processes. The scope of applications of such a system has been extended fro ...
The lack of knowledge regarding air entrainment caused by large jets in hydraulic structures, such as downstream Pelton turbines, has led EDF (Electricité de France) to carry out a test series to optimize the La Coche Power plant. The data extracted from t ...
Analogous to the way the Human Genome Project advanced an array of biological sciences by mapping the human genome, the Materials Genome Initiative aims to enhance our understanding of the fundamentals of materials science by providing the information we n ...
