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Continuous sampling and analysis by on-chip liquid/solid chromatography

Related publications (51)

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Biochemical reaction rates in microfluidic systems are known to be limited by the diffusional transport of reagents, leading often to lowered sensitivity and/or longer detection times in immunoassays. Several methods, including electrically powering electr ...

ROYAL SOC CHEMISTRY2023

Polydimethylsiloxane microstructure-induced acoustic streaming for enhanced ultrasonic DNA fragmentation on a microfluidic chip

Martinus Gijs, Thomas Lehnert, Lin Sun

Next-generation sequencing (NGS) is an essential technology for DNA identification in genomic research. DNA fragmentation is a critical step for NGS and doing this on-chip is of great interest for future integrated genomic solutions. Here we demonstrate fa ...

ROYAL SOC CHEMISTRY2022

Microfluidic is an ensemble of technologies and methods that permits the handling and analysis of minute volumes of samples in short timescales. Since its introduction it revealed a remarkable potential to unveil novel biological mechanisms. The small volu ...

EPFL2022

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We present a novel concept for the controlled trapping and releasing of beads and cells in a PDMS microfluidic channel without obstacles present around the particle or in the channel. The trapping principle relies on a two-level microfluidic configuration: ...

ROYAL SOC CHEMISTRY2021

Ultrasensitive optofluidic enzyme-linked immunosorbent assay by on-chip integrated polymer whispering-gallery-mode microlaser sensors

Jijun He

Optical whispering-gallery-mode (WGM) microcavities offer great promise in ultrasensitive biosensors because of their unique ability to enable resonant recirculation of light to achieve strong light-matter interactions in microscale volumes. However, it re ...

ROYAL SOC CHEMISTRY2020

Modular interface and experimental setup for in-vacuum operation of microfluidic devices

Luis Guillermo Villanueva Torrijo, Annalisa De Pastina, Damien Maillard, Tom Larsen

We report on the design and operation of a world-to-chip microfluidic interface and experimental setup for fluidic micro- and nano-electromechanical systems. The central component of the interface is an engineered polyether ether ketone connector that brin ...

AMER INST PHYSICS2019

The nematode Caenorhabditis elegans is an attractive model organism, owing notably to its short life cycle, genetic tractability, and optical transparency facilitating microscopic observation. This thesis deals with the realization of technological tools f ...

EPFL2018

Portable Memristive Biosensing System as Effective Point-of-Care Device for Cancer Diagnostics

Giovanni De Micheli, Sandro Carrara, Danilo Demarchi, Ioulia Tzouvadaki, Abuduwaili Tuoheti

Memristive biosensors have been proved as excellent candidates for ultrasensitive biosensing. In this work, a novel portable bio-detection system based on memristive biosensors is designed, developed and tested for providing a significantly fast, automatic ...

IEEE2018

CALIBRATION DE CAPTEURS PASSIFS CHEMCATCHERS POUR L'ANALYSE DE MICROPOLLUANTS POLAIRES ET DE STUPEFIANTS DANS DES EAUX USEES

Paul Louis Henri Koblan-Huberson

Dans le but de réaliser la calibration de capteurs passifs de type chemcatchers dans les eaux en entrée de STEP pour une gamme de micropolluants communs et de composés illicites à usage récréatif, la méthode suivante est appliquée : 1) Conditionnement et d ...

2018

This paper presents the development of MEMS gas preconcentrator (GP) for the detection of trace level Volatile Organic Compounds (VOCs). Besides the development of the MEMS gas preconcentrator, we have also worked on the coupling of this preconcentration d ...

Elsevier2014