Test caseIn software engineering, a test case is a specification of the inputs, execution conditions, testing procedure, and expected results that define a single test to be executed to achieve a particular software testing objective, such as to exercise a particular program path or to verify compliance with a specific requirement. Test cases underlie testing that is methodical rather than haphazard. A battery of test cases can be built to produce the desired coverage of the software being tested.
DNA sequencingDNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. Knowledge of DNA sequences has become indispensable for basic biological research, DNA Genographic Projects and in numerous applied fields such as medical diagnosis, biotechnology, forensic biology, virology and biological systematics.
Protein foldingProtein folding is the physical process where a protein chain is translated into its native three-dimensional structure, typically a "folded" conformation, by which the protein becomes biologically functional. Via an expeditious and reproducible process, a polypeptide folds into its characteristic three-dimensional structure from a random coil. Each protein exists first as an unfolded polypeptide or random coil after being translated from a sequence of mRNA into a linear chain of amino acids.
Order topologyIn mathematics, an order topology is a certain topology that can be defined on any totally ordered set. It is a natural generalization of the topology of the real numbers to arbitrary totally ordered sets. If X is a totally ordered set, the order topology on X is generated by the subbase of "open rays" for all a, b in X. Provided X has at least two elements, this is equivalent to saying that the open intervals together with the above rays form a base for the order topology.
Fusion proteinFusion proteins or chimeric (kī-ˈmir-ik) proteins (literally, made of parts from different sources) are proteins created through the joining of two or more genes that originally coded for separate proteins. Translation of this fusion gene results in a single or multiple polypeptides with functional properties derived from each of the original proteins. Recombinant fusion proteins are created artificially by recombinant DNA technology for use in biological research or therapeutics.
Sampling biasIn statistics, sampling bias is a bias in which a sample is collected in such a way that some members of the intended population have a lower or higher sampling probability than others. It results in a biased sample of a population (or non-human factors) in which all individuals, or instances, were not equally likely to have been selected. If this is not accounted for, results can be erroneously attributed to the phenomenon under study rather than to the method of sampling.
Whole genome sequencingWhole genome sequencing (WGS), also known as full genome sequencing, complete genome sequencing, or entire genome sequencing, is the process of determining the entirety, or nearly the entirety, of the DNA sequence of an organism's genome at a single time. This entails sequencing all of an organism's chromosomal DNA as well as DNA contained in the mitochondria and, for plants, in the chloroplast. Whole genome sequencing has largely been used as a research tool, but was being introduced to clinics in 2014.
Integration testingIntegration testing (sometimes called integration and testing, abbreviated I&T) is the phase in software testing in which the whole software module is tested or if it consists of multiple software modules they are combined and then tested as a group. Integration testing is conducted to evaluate the compliance of a system or component with specified functional requirements. It occurs after unit testing and before system testing.
Regression testingRegression testing (rarely, non-regression testing) is re-running functional and non-functional tests to ensure that previously developed and tested software still performs as expected after a change. If not, that would be called a regression. Changes that may require regression testing include bug fixes, software enhancements, changes, and even substitution of electronic components (hardware). As regression test suites tend to grow with each found defect, test automation is frequently involved.
Order theoryOrder theory is a branch of mathematics that investigates the intuitive notion of order using binary relations. It provides a formal framework for describing statements such as "this is less than that" or "this precedes that". This article introduces the field and provides basic definitions. A list of order-theoretic terms can be found in the order theory glossary. Orders are everywhere in mathematics and related fields like computer science. The first order often discussed in primary school is the standard order on the natural numbers e.
