Random coilIn polymer chemistry, a random coil is a conformation of polymers where the monomer subunits are oriented randomly while still being bonded to adjacent units. It is not one specific shape, but a statistical distribution of shapes for all the chains in a population of macromolecules. The conformation's name is derived from the idea that, in the absence of specific, stabilizing interactions, a polymer backbone will "sample" all possible conformations randomly.
Accusative caseThe accusative case (abbreviated ) of a noun is the grammatical case used to receive the direct object of a transitive verb. In the English language, the only words that occur in the accusative case are pronouns: "me", "him", "her", "us", "whom", and "them". For example, the pronoun she, as the subject of a clause, is in the nominative case ("She wrote a book"); but if the pronoun is instead the object of the verb, it is in the accusative case and she becomes her ("Fred greeted her"). For compound direct objects, it would be, e.
ProlineProline (symbol Pro or P) is an organic acid classed as a proteinogenic amino acid (used in the biosynthesis of proteins), although it does not contain the amino group -NH2 but is rather a secondary amine. The secondary amine nitrogen is in the protonated form (NH2+) under biological conditions, while the carboxyl group is in the deprotonated −COO− form. The "side chain" from the α carbon connects to the nitrogen forming a pyrrolidine loop, classifying it as a aliphatic amino acid.
Computational fluid dynamicsComputational fluid dynamics (CFD) is a branch of fluid mechanics that uses numerical analysis and data structures to analyze and solve problems that involve fluid flows. Computers are used to perform the calculations required to simulate the free-stream flow of the fluid, and the interaction of the fluid (liquids and gases) with surfaces defined by boundary conditions. With high-speed supercomputers, better solutions can be achieved, and are often required to solve the largest and most complex problems.
Grammatical caseA grammatical case is a category of nouns and noun modifiers (determiners, adjectives, participles, and numerals) which corresponds to one or more potential grammatical functions for a nominal group in a wording. In various languages, nominal groups consisting of a noun and its modifiers belong to one of a few such categories. For instance, in English, one says I see them and they see me: the nominative pronouns I/they represent the perceiver and the accusative pronouns me/them represent the phenomenon perceived.
Peptide synthesisIn organic chemistry, peptide synthesis is the production of peptides, compounds where multiple amino acids are linked via amide bonds, also known as peptide bonds. Peptides are chemically synthesized by the condensation reaction of the carboxyl group of one amino acid to the amino group of another. Protecting group strategies are usually necessary to prevent undesirable side reactions with the various amino acid side chains. Chemical peptide synthesis most commonly starts at the carboxyl end of the peptide (C-terminus), and proceeds toward the amino-terminus (N-terminus).
Protein dynamicsProteins are generally thought to adopt unique structures determined by their amino acid sequences. However, proteins are not strictly static objects, but rather populate ensembles of (sometimes similar) conformations. Transitions between these states occur on a variety of length scales (tenths of Å to nm) and time scales (ns to s), and have been linked to functionally relevant phenomena such as allosteric signaling and enzyme catalysis.
Nuclear Overhauser effectThe nuclear Overhauser effect (NOE) is the transfer of nuclear spin polarization from one population of spin-active nuclei (e.g. 1H, 13C, 15N etc.) to another via cross-relaxation. A phenomenological definition of the NOE in nuclear magnetic resonance spectroscopy (NMR) is the change in the integrated intensity (positive or negative) of one NMR resonance that occurs when another is saturated by irradiation with an RF field. The change in resonance intensity of a nucleus is a consequence of the nucleus being close in space to those directly affected by the RF perturbation.
Vocative caseIn grammar, the vocative case (abbreviated ) is a grammatical case which is used for a noun that identifies a person (animal, object, etc.) being addressed, or occasionally for the noun modifiers (determiners, adjectives, participles, and numerals) of that noun. A vocative expression is an expression of direct address by which the identity of the party spoken to is set forth expressly within a sentence.
Software configuration managementIn software engineering, software configuration management (SCM or S/W CM) is the task of tracking and controlling changes in the software, part of the larger cross-disciplinary field of configuration management. SCM practices include revision control and the establishment of baselines. If something goes wrong, SCM can determine the "what, when, why and who" of the change. If a configuration is working well, SCM can determine how to replicate it across many hosts.
