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Regulation of sedimentation rate shapes the evolution of multicellularity in a close unicellular relative of animals

Related publications (31)

Self-supervised Dense Representation Learning for Live-Cell Microscopy with Time Arrow Prediction

Martin Weigert, Benjamin Tobias Gallusser, Max Stieber

State-of-the-art object detection and segmentation methods for microscopy images rely on supervised machine learning, which requires laborious manual annotation of training data. Here we present a self-supervised method based on time arrow prediction pre-t ...

Springer International Publishing Ag2023

Fish Diversity in Relation to Littoral Habitats in Three Basins of Lake Kivu (East Africa)

Alfred Johny Wüest

In total, 28 of the 29 fish species reported from the Lake Kivu basin occur in the littoral zone of the lake, but information about their structure, occurrence, and the habitats affecting their distribution is largely lacking. The lake's inshore area is po ...

MDPI2023

Cellularization across eukaryotes: Conserved mechanisms and novel strategies

Omaya Pierre Dudin

Many eukaryotes form multinucleated cells during their devel-opment. Some cells persist as such during their lifetime, others choose to cleave each nucleus individually using a specialized cytokinetic process known as cellularization. What is cellula-rizat ...

CURRENT BIOLOGY LTD2023

Whole-genome doubling drives oncogenic loss of chromatin segregation

Elisa Oricchio, Daniele Tavernari, Natalya Katanayeva, Ruxandra-Andreea Lambuta, Juan Diaz Miyar, Giovanni Ciriello

Whole-genome doubling (WGD) is a recurrent event in human cancers and it promotes chromosomal instability and acquisition of aneuploidies(1-8). However, the three-dimensional organization of chromatin in WGD cells and its contribution to oncogenic phenotyp ...

NATURE PORTFOLIO2023

Development of multiplexed single-molecule imaging techniques to study chromatin invasion dynamics of chromatin effector proteins

Kristina Makasheva

DNA-binding proteins physically interact with the DNA and directly affect genomic functions. The eukaryotic genome is compacted into chromatin, limiting the DNA access to nuclear factors. In this Ph.D. thesis, I explored the dynamic mechanisms, that allow ...

EPFL2023

Cortical cell assemblies and their underlying connectivity: an in silico study

Michael Reimann, András Ecker, Sirio Bolaños Puchet, James Bryden Isbister, Daniela Egas Santander

Recent developments in experimental techniques have enabled simultaneous recordings from thousands of neurons, enabling the study of functional cell assemblies. However, determining the patterns of synaptic connectivity giving rise to these assemblies rema ...

2024

Whole genome doubling promotes tumorigenesis through loss of chromatin segregation and compartment repositioning

Ruxandra-Andreea Lambuta

Whole genome doubling (WGD) events are drivers of genetic innovation across vertebrate evolution. While generally detrimental to mammalian organisms, WGDs are crucial in the development of various plants and fungi, as well as for the terminal differentiati ...

EPFL2023

Sperm-contributed centrioles segregate stochastically into blastomeres of 4-cell stage Caenorhabditis elegans embryos

Pierre Gönczy, Fernando Romero Balestra

Whereas both sperm and egg contribute nuclear genetic material to the zygote in metazoan organisms, the inheritance of other cellular constituents is unequal between the 2 gametes. Thus, 2 copies of the centriole are contributed solely by the sperm to the ...

GENETICS SOCIETY AMERICA2023

Exploring the interplay of molecular pattern and valency for selective interactions at the bio-interface

Kaltrina Paloja

Cell-cell communication is fundamental for immune balance. Multivalent interactions of surface receptors at immune interfaces drive specific communication, with stimulatory and inhibitory signals guiding the immune outcome. Notably, the valency, affinity, ...

EPFL2023

Regulation of sedimentation rate shapes the evolution of multicellularity in a close unicellular relative of animals

Self-supervised Dense Representation Learning for Live-Cell Microscopy with Time Arrow Prediction

Fish Diversity in Relation to Littoral Habitats in Three Basins of Lake Kivu (East Africa)

Cellularization across eukaryotes: Conserved mechanisms and novel strategies

Whole-genome doubling drives oncogenic loss of chromatin segregation

Development of multiplexed single-molecule imaging techniques to study chromatin invasion dynamics of chromatin effector proteins

Cortical cell assemblies and their underlying connectivity: an in silico study

Whole genome doubling promotes tumorigenesis through loss of chromatin segregation and compartment repositioning

Sperm-contributed centrioles segregate stochastically into blastomeres of 4-cell stage Caenorhabditis elegans embryos

Exploring the interplay of molecular pattern and valency for selective interactions at the bio-interface

Graph Chatbot

Self-supervised Dense Representation Learning for Live-Cell Microscopy with Time Arrow Prediction

Fish Diversity in Relation to Littoral Habitats in Three Basins of Lake Kivu (East Africa)

Cellularization across eukaryotes: Conserved mechanisms and novel strategies

Whole-genome doubling drives oncogenic loss of chromatin segregation

Development of multiplexed single-molecule imaging techniques to study chromatin invasion dynamics of chromatin effector proteins

Cortical cell assemblies and their underlying connectivity: an in silico study

Whole genome doubling promotes tumorigenesis through loss of chromatin segregation and compartment repositioning

Sperm-contributed centrioles segregate stochastically into blastomeres of 4-cell stage Caenorhabditis elegans embryos

Towards understanding centriole elimination

Exploring the interplay of molecular pattern and valency for selective interactions at the bio-interface

Towards understanding centriole elimination