Publication

Microencapsulated human mesenchymal stem cells decrease liver fibrosis in mice

Related publications (31)

Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP

Henning Paul-Julius Stahlberg, Dongchun Ni

BSEP (ABCB11) is an ATP-binding cassette transporter that is expressed in hepatocytes and extrudes bile salts into the canaliculi of the liver. BSEP dysfunction, caused by mutations or induced by drugs, is frequently associated with severe cholestatic live ...

Nature Portfolio2023

Engineered substrates incapable of induction of chondrogenic differentiation compared to the chondrocyte imprinted substrates

Philippe Renaud, Shahin Bonakdar, Leila Montazeri, Zahrasadat Ghazali

It is well established that surface topography can affect cell functions. However, finding a reproducible and reliable method for regulating stem cell behavior is still under investigation. It has been shown that cell imprinted substrates contain micro- an ...

IOP Publishing Ltd2023

Spatiotemporal Metabolic Liver Zonation and Consequences on Pathophysiology

Felix Naef, Tomaz Martini

Hepatocytes are the main workers in the hepatic factory, managing metabolism of nutrients and xenobiotics, production and recycling of proteins, and glucose and lipid homeostasis. Division of labor between hepatocytes is critical to coordinate complex comp ...

ANNUAL REVIEWS2023

Programming of Multicellular Patterning with Mechano-Chemically Microstructured Cell Niches

Pierre Osteil

Multicellular patterning of stem-cell-derived tissue models is commonly achieved via self-organizing activities triggered by exogenous morphogenetic stimuli. However, such tissue models are prone to stochastic behavior, limiting the reproducibility of cell ...

WILEY2023

Human PBMCs Form Lipid Droplets in Response to Spike Proteins

Florian Maria Wurm, Guillaume Raussin

Intracellular lipid droplets (LDs) can accumulate in response to inflammation, metabolic stresses, and other physiological/pathological processes. Herein, we investigated whether spike proteins of SARS-CoV-2 induce LDs in human peripheral blood mononuclear ...

MDPI2023

Novel quantitative bioengineered tools to track human bone marrow niche cellular constituents in health and disease

Rita Sarkis

Acute leukemia has a high mortality rate of approximately 50%, and current methods are not effective in predicting disease progression and relapse. To improve our understanding of hematopoiesis and develop new markers for predicting disease relapse in dead ...

EPFL2023

A spatially multiplexed voltammetric magneto-sandwich assay involving Fe3O4/Fe-based metal-organic framework for dual liver cancer biomarkers

Hubert Girault, Milica Jovic

Voltammetric sandwich assays were constructed by integrating capture bioreceptors-conjugated magnetic nanocomposites, namely Fe3O4/MIL-101(Fe)-(NH)(CO)-COOH (FO/MOF) and alkaline phosphatase (ALP)labeled detection antibodies on an eight-well screen-printed ...

ELSEVIER SCIENCE SA2023

Investigating the effect of inflammation on the progression of B-cell lymphoma dissemination in the sentinel lymph node

Daniel Molina Romero

Lymphomas are a group of heterogeneous blood cancers that arise from lymphocytes. The two primary clinical classifications of lymphomas are Hodgkin's lymphoma (HL), and non-Hodgkin's lymphoma (NHL). In particular, B-cell lymphoma refers to the malignancies ...

EPFL2023

ISSCR standards for the use of human stem cells in basic research

Matthias Lütolf

The laboratory culture of human stem cells seeks to capture a cellular state as an in vitro surrogate of a biological system. For the results and outputs from this research to be accurate, meaning-ful, and durable, standards that ensure reproducibility and ...

Cell Press2023

Microencapsulated human mesenchymal stem cells decrease liver fibrosis in mice

Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP

Engineered substrates incapable of induction of chondrogenic differentiation compared to the chondrocyte imprinted substrates

Spatiotemporal Metabolic Liver Zonation and Consequences on Pathophysiology

Programming of Multicellular Patterning with Mechano-Chemically Microstructured Cell Niches

Human PBMCs Form Lipid Droplets in Response to Spike Proteins

Novel quantitative bioengineered tools to track human bone marrow niche cellular constituents in health and disease

A spatially multiplexed voltammetric magneto-sandwich assay involving Fe3O4/Fe-based metal-organic framework for dual liver cancer biomarkers

Investigating the effect of inflammation on the progression of B-cell lymphoma dissemination in the sentinel lymph node

ISSCR standards for the use of human stem cells in basic research

Graph Chatbot

Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP

Engineered substrates incapable of induction of chondrogenic differentiation compared to the chondrocyte imprinted substrates

Spatiotemporal Metabolic Liver Zonation and Consequences on Pathophysiology

Programming of Multicellular Patterning with Mechano-Chemically Microstructured Cell Niches

Human PBMCs Form Lipid Droplets in Response to Spike Proteins

Novel quantitative bioengineered tools to track human bone marrow niche cellular constituents in health and disease

A spatially multiplexed voltammetric magneto-sandwich assay involving Fe3O4/Fe-based metal-organic framework for dual liver cancer biomarkers

Investigating the effect of inflammation on the progression of B-cell lymphoma dissemination in the sentinel lymph node

Disruption of stem cell niche-confined R-spondin 3 expression leads to impaired hematopoiesis

ISSCR standards for the use of human stem cells in basic research

Disruption of stem cell niche-confined R-spondin 3 expression leads to impaired hematopoiesis