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Erythrocyte's aging in microgravity highlights how environmental stimuli shape metabolism and morphology

Related publications (29)

Virtual Zero Gravity Impact on Internal Gravity Model

Ronan Boulic, Bruno Herbelin, Elisa Canzoneri

This project investigates the impact of a virtual zero gravity experience on the human gravity model. In the planned experiment, subjects are immersed with HMD and full body motion capture in a virtual world exhibiting either normal gravity or the apparent ...

Ieee Computer Soc2017

Integration of Metabolic, Regulatory and Signaling Networks Towards Analysis of Perturbation and Dynamic Responses

Vassily Hatzimanikatis, Meriç Ataman, Vikash Kumar Pandey, Anush Chiappino-Pepe

The expanding generation of dynamic biological data requires approaches that integrate and analyze information from different types of cellular processes –metabolism, regulation, and signaling–, and ultimately increase our insights into the cell behavior u ...

2017

Ribosome profiling and dynamic regulation of translation in mammals

Felix Naef, Cédric Gobet

Protein synthesis is an energy-demanding cellular process. Consequently, a well-timed, fine-tuned and plastic regulation of translation is needed to adjust and maintain cell states under dynamically changing environments. Genome-wide monitoring of translat ...

Elsevier2017

Miniaturized single-cell analyses for biomedical applications

Loïc Arvind Roger Arm

Numerous diseases affecting living beings have as a cause a modification of gene expression resulting in anomalous expression of proteins in up- or down-regulated fashion, with altered functions or expression of proteins that are not present in the cell in ...

EPFL2017

Multisensory interactions in peripersonal space and their contributions to bodily self-consciousness

Petr Grivaz

What is the relevance of the body and body-transformed sensory information for subjective experience? In the last two decades, paradigms from cognitive neuroscience have demonstrated that the subjective sensations of possessing a body (body ownership, BO), ...

EPFL2017

Mechanical and Functional Study of Cell Physiology at the Nanoscale

Pascal Damian Odermatt

By live-cell imaging of biological samples dynamic cellular processes can be resolved. Fluorescence microscopy (FM) and atomic force microscopy (AFM) are both capable of imaging live cells. By combining these techniques structural as well as functional inf ...

EPFL2016

Scaling laws for jets of single cavitation bubbles

Mohamed Farhat, Nicolas Dorsaz, Danail Obreschkow, Philipp Kobel, Outi Supponen, Marc Tinguely

Fast liquid jets, called micro-jets, are produced within cavitation bubbles experiencing an aspherical collapse. Here we review micro-jets of different origins, scales and appearances, and propose a unified framework to describe their dynamics by using an ...

Cambridge University Press2016

Automated tracking of temporal displacements of a red blood cell obtained by time-lapse digital holographic microscopy

Benjamin Rappaz

Red blood cell (RBC) phase images that are numerically reconstructed by digital holographic microscopy (DHM) can describe the cell structure and dynamics information beneficial for a quantitative analysis of RBCs. However, RBCs investigated with time-lapse ...

Optical Soc Amer2016

Deciphering Metabolic Regulation of Hematopoietic Stem Cell Fate

Mukul Girotra

Hematopoietic stem cells (HSCs) are responsible for life-long production of all mature blood cells. This unique characteristic makes them an ideal candidate for cell-based therapies to treat various hematological malignancies. Their extensive use in the cl ...

EPFL2015