Synthetic calibrators for the analysis of sulfoconjugated metanephrines in urine: hydrolysis conditions revisited

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Static and dynamic properties of non-collinear quantum antiferromagnets explored by neutron scattering

This thesis is devoted to the investigation of static and dynamic properties of two different sets of quantum magnets with neutron scattering techniques and the help of linear spin wave theory. Both systems are copper-based with spin-1/2, which makes them ...

EPFL2021

Modelling the Intracellular Environment under Uncertainty, from Post-translational Modification to Metabolic Networks

Robin Alexander Denhardt-Eriksson

Modelling and analysis of biological systems is crucial in order to quantitatively explain and predict their behaviour. The importance of modelling in systems biology becomes even more evident when tackling complex, large systems. Approaches that rely on ...

EPFL2021

An Overview of Serum Albumin Interactions with Biomedical Alloys

Stefano Mischler, Anna Neus Igual Muñoz, Oksana Klok

Understanding the interactions between biomedical alloys and body fluids is of importance for the successful and safe performance of implanted devices. Albumin, as the first protein that comes in contact with an implant surface, can determine the biocompat ...

2020

Experimental study of impulse waves generated by viscoplastic fluid

Zhenzhu Meng

Landslide-generated waves, also called impulse waves, occur as a result of the intrusion of landslides (such as rock falls, debris flows, and avalanches) into bodies of water (such as lakes, reservoirs, and seas). The objective of this thesis was to study ...

EPFL2020

Quantifying the information impact of future searches for exoplanetary biosignatures

Claudio Grimaldi

One of the major goals for astronomy in the next decades is the remote search for biosignatures (i.e., the spectroscopic evidence of biological activity) in exoplanets. Here we adopt a Bayesian statistical framework to discuss the implications of such futu ...

National Academy of Sciences2020

The needle model: A new model for the main hydration peak of alite

Karen Scrivener, Alexandre Reda Constantin William Caleb Ouzia

This article presents a new model for the main hydration peaks of tricalcium silicate and alite on the assumption that C-S-H nucleates and grows as needles. The model relies only on directly observable quantities and reproduces the transition from the acce ...

Pergamon-Elsevier Science Ltd2019

A biosensor for measuring NAD(+) levels at the point of care

Johan Auwerx, Kai Johnsson, Luc Patiny, Elena Katsyuba, Qiuliyang Yu, Lin Xue

The cellular level of nicotinamide adenine dinucleotide (NAD(+)), through its different functions, affects cellular metabolism and signalling(1-3). A decrease in the NAD(+) content has been associated with various pathologies and physiological aging(4,5), ...

NATURE PUBLISHING GROUP2019

A new analysis approach for T-2 relaxometry myelin water quantification: Orthogonal Matching Pursuit

Guillaume Jean Op 't Veld

Purpose: In vivo myelin quantification can provide valuable noninvasive information on neuronal maturation and development, as well as insights into neurological disorders. Multiexponential analysis of multiecho T-2 relaxation is a powerful and widely appl ...

Wiley2019

Verified Functional Programming

Nicolas Charles Yves Voirol

In this thesis, we present Stainless, a verification system for an expressive subset of the Scala language. Our system is based on a dependently-typed language and an algorithmic type checking procedure which ensures total correctness. We rely on SMT solve ...

EPFL2019

Production and characterization of stabilized lignin

Masoud Talebi Amiri

Lignocellulosic biomass is a sustainable source of renewable carbon, and it is the most abundant form of terrestrial biomass. The three main constituents of lignocellulosic biomass are cellulose, hemicellulose, and lignin. The monomers from these biopolyme ...

EPFL2019

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