On the role of human mobility in the spread of cholera epidemics: towards an epidemiological movement ecology

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Modeling infectious disease dynamics towards informed public health interventions, with applications on COVID-19 and cholera

Emerging and existing infectious diseases pose a constant threat to individuals and communities across the world. In many cases, the burden of these diseases is preventable through public health interventions. However, taking the right decisions and design ...

EPFL2021

Transparent composite nano-fibre based multi-layer textile

Klaus Benedikt Schönenberger, Thierry Pelet

A composite multi-layer textile (1), comprising at least one nanofibre layer (11) with nanofibres with diameters below 100nm and one support layer (12) with microfibres with diameters below three microns, wherein the layers (11, 12) were produced by electr ...

2021

Private and Secure Distributed Learning

Georgios Damaskinos

The ever-growing number of edge devices (e.g., smartphones) and the exploding volume of sensitive data they produce, call for distributed machine learning techniques that are privacy-preserving. Given the increasing computing capabilities of modern edge de ...

EPFL2020

Comparison of chitin‐induced natural transformation in pandemic Vibrio cholerae O1 El Tor strains

Melanie Blokesch, Sandrine Stutzmann

The human pathogen Vibrio cholerae serves as a model organism for many important processes ranging from pathogenesis to natural transformation, which has been extensively studied in this bacterium. Previous work has deciphered important regulatory circuits ...

2020

Interbacterial competition and anti‐predatory behavior of environmental Vibrio cholerae strains

Melanie Blokesch, Natalia Carolina Drebes Dorr

Vibrio cholerae isolates responsible for cholera pandemics represent only a small portion of the diverse strains belonging to this species. Indeed, most V. cholerae are encountered in aquatic environments. To better understand the emergence of pandemic lin ...

2020

Species conservation in the face of global environmental changes: surface-based modelling of geo-environmental data to identify vulnerable populations

Estelle Rochat

Human activities are resulting in many land-use changes, particularly due to urbanisation and intensification of agricultural practices. Because of these changes, in addition to climate change, many species are facing habitat degradation. In order to avoid ...

EPFL2020

Rainfall as a driver of epidemic cholera: Comparative model assessments of the effect of intra-seasonal precipitation events

Andrea Rinaldo, Damiano Pasetto, Francisco Javier Perez Saez, Joseph Chadi Benoit Lemaitre, Carla Sciarra

The correlation between cholera epidemics and climatic drivers, in particular seasonal tropical rainfall, has been studied in a variety of contexts owing to its documented relevance. Several mechanistic models of cholera transmission have included rainfall ...

2019

Vibrio cholerae filamentation promotes chitin surface attachment at the expense of competition in biofilms

Alexandre Louis André Persat

Collective behavior in spatially structured groups, or biofilms, is the norm among microbes in their natural environments. Though biofilm formation has been studied for decades, tracing the mechanistic and ecological links between individual cell morpholog ...

National Academy of Sciences2019

Two nanomachines drive evolution in diverse Vibrio species

Noémie Matthey

Horizontal gene transfer (HGT) has a major impact on bacterial evolution, leading to acquisition or deletion of genes and gene clusters, including those encoding antibiotic resistances and virulence factors. HGT therefore contributes to pathogen emergence, ...

EPFL2019

Reliable and Robust Cyber-Physical Systems for Real-Time Control of Electric Grids

Wajeb Saab

Real-time control of electric grids is a novel approach to handling the increasing penetration of distributed and volatile energy generation brought about by renewables. Such control occurs in cyber-physical systems (CPSs), in which software agents maintai ...

EPFL2019

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