Optical characterization of high numerical aperture microlenses for quality assessment and fabrication process optimization

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Adaptive optics enables multimode 3D super-resolution microscopy via remote focusing

Aleksandra Radenovic, Sanjin Marion, Vytautas Navikas, Adrien Charles-François Raymond Descloux, Kristin Stefanie Grussmayer

A variety of modern super-resolution micro-scopy methods provide researchers with previouslyinconceivable biological sample imaging opportunities ata molecular resolution. All of these techniques excel atimaging samples that are close to the coverslip, how ...

2021

Correction of spherical surface measurements by confocal microscopy

Toralf Scharf, Wilfried Noell, Jeremy Béguelin

Refractive microlenses are nowadays widely used in optical systems. Characterizing their surface is essential to ensure their quality and to optimize their fabrication process. This is realized by optical surface profilers thanks to their vertical resoluti ...

2020

On the assessment of aspheric refractive microlenses

Jeremy Béguelin

Refractive microlenses and microlens arrays are key components for many applications such as optical data communication, laser and medical devices, or cameras. In particular, refractive micro-optics enables the miniaturization of high-tech systems but also ...

EPFL2020

3D nanometrology of transparent objects by phase calibration of a basic bright-field microscope for multiple illumination apertures

Martinus Gijs, Daniel Migliozzi, Bingying Zhao

Optical retrieval of the structure of transparent objects at the nanoscale requires adapted techniques capable of probing their interaction with light. Here, we considered a method based on calibration of the defocusing with partially coherent illumination ...

2020

Light pattern generation with hybrid refractive microoptics under Gaussian beam illumination

Toralf Scharf, Maryam Yousefi

The generation of wide-angle diffraction patterns can be done in different ways using either thin diffractive optical elements with small features sizes or arrays of microoptics with large optical paths that are thick diffractive optical elements. Our aim ...

2020

Koehler integrator device and application thereof in a multi-focal confocal microscope

Suliana Manley, Kyle Michael Douglass, Dora Mahecic

A Koehler integrator device (10) comprises a collimating lens (11) being arranged for collimating a light field created by an incoherent or partially coherent light source, a pair of planar first and second micro-lens arrays (12, 13) being arranged for rel ...

2020

Lens aberration compensation in interference microscopy

Yves Bellouard, Jakub Drs

Emergence of products that feature functional surfaces with complex geometries, such as freeform optics in consumer electronics and augmented reality and virtual reality, requires high-accuracy non-contact surface measurement. However, large discrepancies ...

2020

Tolerancing the surface form of aspheric microlenses manufactured by wafer-level optics techniques

Toralf Scharf, Wilfried Noell, Jeremy Béguelin

Tolerancing is an important step toward the fabrication of high-quality and cost-effective lens surfaces. It is critical for wafer-level optics, when up to tens of thousands microlenses are fabricated in parallel and whose surfaces cannot be formed individ ...

OPTICAL SOC AMER2020

Development of novel experimental and computational methods for three-dimensional coherent and super-resolution microscopy

Adrien Charles-François Raymond Descloux

Optical microscopy is one widely used tool to study cell functions and the interaction of molecules at a sub-cellular level. Optical microscopy techniques can be broadly divided into two categories: partially coherent and incoherent. Coherent microscopy te ...

EPFL2020

Three-dimensional tomography of red blood cells using deep learning

Demetri Psaltis, Joowon Lim, Ahmed Ayoub

We accurately reconstruct three-dimensional (3-D) refractive index (RI) distributions from highly ill-posed two-dimensional (2-D) measurements using a deep neural network (DNN). Strong distortions are introduced on reconstructions obtained by the Wolf tran ...

2020

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3D nanometrology of transparent objects by phase calibration of a basic bright-field microscope for multiple illumination apertures

Martinus Gijs, Daniel Migliozzi, Bingying Zhao

2020

Development of novel experimental and computational methods for three-dimensional coherent and super-resolution microscopy

Adrien Charles-François Raymond Descloux

EPFL2020

Tolerancing the surface form of aspheric microlenses manufactured by wafer-level optics techniques

Toralf Scharf, Wilfried Noell, Jeremy Béguelin

OPTICAL SOC AMER2020