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The 12-lead electrocardiogram (ECG) is a major diagnostic test for cardiovascular diseases and enhanced automated analysis tools might lead to more reliable diagnosis and improved clinical practice. Deep neural networks are models composed of stacked trans ...
Rationale: Hypertension represents a major risk factor for stroke, myocardial infarction, and heart failure and affects 30% of the adult population. Mitochondrial dysfunction contributes to hypertension, but specific mechanisms are unclear. The mitochondri ...
Cardiac and aortic characteristics are crucial for cardiovascular disease detection. However, noninvasive estimation of aortic hemodynamics and cardiac contractility is still challenging. This paper investigated the potential of estimating aortic systolic ...
In this thesis, I focus on monitoring of patients suffering from cardiovascular and neurological diseases through the use of wearable devices. The main diseases considered in this thesis are atrial fibrillation (AF), myocardial infarction (MI), and epileps ...
Brain natriuretic peptide (BNP) treatment increases heart function and decreases heart dilation after myocardial infarction (MI). Here, we investigated whether part of the cardioprotective effect of BNP in infarcted hearts related to improved neovascularis ...
Despite the improving imaging techniques, it remains challenging to produce magnetic resonance (MR) imaging fingerprints depicting severity of acute ischemia. The aim of this study was to evaluate the potential of the overall high-field H-1 MR Spectroscopy ...
In the framework of efficient partitioned numerical schemes for simulating multiphysics PDE problems, we propose using intergrid transfer operators based on radial basis functions to accurately exchange information among different PDEs defined in the same ...
Heart auscultation is a widely used technique for diagnosing cardiac abnormalities. In that context, capturing of phonocardiogram (PCG) signals and automatically monitoring of the heart by identifying S1 and S2 complexes is an emerging field. One of the fi ...
In this paper, we present a mathematical model able to simulate the cardiac function. We first describe the basic physical principles behind the mathematical equations, then we illustrate a few examples of application to problems of clinical relevance. ...
Aim Arginase 2 (ARG2) is a mitochondrial enzyme that catalyses hydrolysis ofl-arginine into urea andl-ornithine. In the kidney, ARG2 is localized to the S3 segment of the proximal tubule. It has been shown that expression and activity of this enzyme are up ...
