Catégorie
Maladie cardiovasculaire
Publications associées (1 000)
Implementation of an epicardial implantable MEMS sensor for continuous and real-time postoperative assessment of left ventricular activity in adult minipigs over a short- and long-term period
The sensing of left ventricular (LV) activity is fundamental in the diagnosis and monitoring of cardiovascular health in high-risk patients after cardiac surgery to achieve better short- and long-term outcome. Conventional approaches rely on noninvasive me ...
Aip Publishing2024An integrated heart-torso electromechanical model for the simulation of electrophysiological outputs accounting for myocardial deformation
Alfio Quarteroni, Francesco Regazzoni
When generating in-silico clinical electrophysiological outputs, such as electrocardiograms (ECGs) and body surface potential maps (BSPMs), mathematical models have relied on single physics, i.e. of the cardiac electrophysiology (EP), neglecting the role o ...
Elsevier Science Sa2024The role of computational methods in cardiovascular medicine: a narrative review
Alfio Quarteroni, Luca Dede', Christian Vergara, Stefano Pagani
Background and Objective: Computational models of the cardiovascular system allow for a detailed and quantitative investigation of both physiological and pathological conditions, thanks to their ability to combine clinical-possibly patient-specific-data wi ...
Ame Publishing Company2024Whole-heart electromechanical simulations using Latent Neural Ordinary Differential Equations
Alfio Quarteroni, Francesco Regazzoni, Luca Dede'
Cardiac digital twins provide a physics and physiology informed framework to deliver personalized medicine. However, high-fidelity multi-scale cardiac models remain a barrier to adoption due to their extensive computational costs. Artificial Intelligence-b ...
Nature Portfolio2024Novel theory and potential applications of central diastolic pressure decay time constant
Nikolaos Stergiopoulos, Georgios Rovas, Sokratis Anagnostopoulos, Vasiliki Bikia, Patrick Segers
Central aortic diastolic pressure decay time constant ( ) is according to the two-element Windkessel model equal to the product of total peripheral resistance (R) times total arterial compliance (C ). As such, it is related to arterial stiffness, which has ...
2024Apparatus for non-invasively computing cardio-vasculature parameters using morphology of uncalibrated pressure wave signal
Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia
Systems and apparatus are provided for using a non-invasively monitored uncalibrated pressure signal from a patient to compute cardiac output and other cardio-vascular parameters, thereby providing safe, effective, reliable and low cost monitoring of patie ...
2024A comprehensive stroke risk assessment by combining atrial computational fluid dynamics simulations and functional patient data
Stroke, a major global health concern often rooted in cardiac dynamics, demands precise risk evaluation for targeted intervention. Current risk models, like the CHA 2 DS 2 -VASc \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepa ...
Nature Portfolio2024Fast-Response Variable-Stiffness Magnetic Catheters for Minimally Invasive Surgery
Dario Floreano, Yegor Piskarev, Jun Shintake, Yi Sun, Matteo Righi
In minimally invasive surgery, such as cardiac ablation, magnetically steered catheters made of variable-stiffness materials can enable higher dexterity and higher force application to human tissue. However, the long transition time between soft and rigid ...
2024Comparing various AI approaches to traditional quantitative assessment of the myocardial perfusion in [82Rb] PET for MACE prediction
Julien René Pierre Fageot, Adrien Raphaël Depeursinge, Daniel Abler
Assessing the individual risk of Major Adverse Cardiac Events (MACE) is of major importance as cardiovascular diseases remain the leading cause of death worldwide. Quantitative Myocardial Perfusion Imaging (MPI) parameters such as stress Myocardial Blood F ...
Nature Portfolio2024Mechanisms and functions of protein S-acylation
Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami, Francisco De Magalhães Sarmento R De Mesquita
Over the past two decades, protein S-acylation (often referred to as S-palmitoylation) has emerged as an important regulator of vital signalling pathways. S-Acylation is a reversible post-translational modification that involves the attachment of a fatty a ...
Berlin2024