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Ageing is associated with marked changes in sleep timing, structure and electroencephalographic (EEG) activity. Older people exhibit less slow-wave and spindle activity during non-rapid eye movement (NREM) sleep, together with attenuated levels of rapid ey ...
The circadian rhythms of melatonin and body temperature are set to an earlier hour in women than in men, even when the women and men maintain nearly identical and consistent bedtimes and wake times. Moreover, women tend to wake up earlier than men and exhi ...
The design of wearable systems comes with constraints in computational and power resources. We describe the development of customized hardware for the wearable discrimination of human sleep and wake based on cardio-respiratory signals. The device was desig ...
Within the last decades it became evident that light through the eyes is essential for both visual and non-visual functions. One of the most important non-visual functions of light is the daily entrainment of the circadian clock by environmental light cond ...
Mammalian physiology has to adapt to daily alternating periods during which animals either forage and feed or sleep and fast. The adaptation of physiology to these oscillations is controlled by a circadian timekeeping system, in which a master pacemaker in ...
The intensive use of daylight in buildings is beneficial at many levels: it provides sufficient levels of illumination to perform working activities throughout the day and it reduces the use of artificial light, which in turn leads to lower electricity con ...
Evening bright light exposure is reported to ameliorate daytime sleepiness and age-related sleep complaints, and also delays the timing of circadian rhythms. We tested whether evening light exposure given to older adults with sleep–wake complaints would de ...
The mammalian circadian clock uses interlocked negative feedback loops in which the heterodimeric basic helix-loop-helix transcription factor BMAL1/CLOCK is a master regulator. While there is prominent control of liver functions by the circadian clock, the ...
Virtually every cell in our body tracks daily time using an endogenous mechanism called the circadian clock, which has a period of about 24 hours. This timing system offers a selective advantage by enabling organisms to anticipate periodic changes in envir ...
Visual comfort is a key element at work places and at home. Besides task illuminance and color rendering it is the indoor light distribution, which strongly impacts visual comfort. We aimed to show possible relations between subjective and objective visual ...