Hilal Lashuel2012-2013 Visiting Professor, Standford University. Stanford School of Medicine
2011- Associate Professor of Life Sciences-Brain Mind Institute-EPFL
Dir. Laboratory of Chemical Biology of Neurodegeneration
2005-2011 Assistant Professor of Life Sciences-Brain Mind Institute-EPFL
Dir. Laboratory of Molecular Neurobiology and Neuroproteomics
2005-2008 Director- EPFL Proteomic Core Facility
2002-2004 Instructor of Neurology- Harvard Medical School and Brigham and Women's
Hospital
2001-2002 Sabbatical Fellow- Laboratory for Drug Discovery in Neurodegeneration
Harvard Medical School,
2001-2002 Post-doctoral Fellow- Center for Neurologic Diseases
Harvard Medical School and Brigham and Women's Hospital
Advisor- Prof. Peter T. Lansbury
2000-2001 Research Scientist, The Picower Institute for Medical Research, Great Neck
New York
1994-2000 PhD Student; Texas A&M University and the Scripps Research Institute
Advisor- Prof. Jeffery W. Kelly
1990-1994 B.S. City University of New York, Brooklyn College
Dr. Hilal A. Lashuel received his B.Sc. degree in chemistry from the City University of New York in 1994 and completed his doctoral studies at Texas A&M University and the Scripps Research Institute in 2000. After obtaining his doctoral degree, he became a research fellow at the Picower Institute for Medical Research in Long Island New York. In 2001, he moved to Harvard Medical School and the Brigham and Women's Hospital as a research fellow in the Center for Neurologic Diseases and was later promoted to an instructor in neurology at Harvard Medical School. During his tenure (2001-2004) at Harvard Medical School his work focused on understanding the mechanisms of protein misfolding and fibrillogenesis and the role of these processes in the pathogenesis of Parkinson's and Alzheimer's disease. In 2005 Dr. Lashuel moved Switzerland to join the Brain Mind Institute at the Swiss Federal Institute of Technology Lausanne as a tenure-track assistant professor in neurosciences. Currently, Dr. Lashuel is an associate professor of life sciences and the director of the laboratory of molecular and chemical biology of neurodegeneration. (http://lashuel-lab.epfl.ch/).
Research efforts in the Lashuels laboratory focus on understanding the molecular mechanisms of neurodegeneration and developing novel strategies to diagnose and treat neurodegenerative diseases such as Alzheimers and Parkinsons disease. Research in the Lashuel lab is funded by several international funding agencies and foundations, including the Swiss National Science Foundation, European FP7 program (Marie Curie and ERC grants), Human Science Frontiers, Strauss Foundation, Cure the Huntingtons disease foundation and Michael J Fox foundation and is supported by collaborations with pharmaceutical and biotech companies (http://lashuel-lab.epfl.ch/page-50538-en.html), Nestle, Merck-Serono, AC Immune and Johnson and Johnson.
Dr. Lashuels research has resulted in the characterization of novel quaternary structure intermediates on the amyloid pathway, identification of potential therapeutic targets, and new hypotheses concerning the mechanisms of pathogenesis in Alzheimers disease, Parkinsons disease and related disorders. Dr. Lashuel scientific contribution to this field includes i) more than100 publications in major peer reviewed journals including Nature journals, Cell, PNAS, JBC, J. Neuroscience JACS, and Angewandtie Chemie; ii) three patents on novel strategies for preventing protein aggregation and treating autoimmune and inflammatory diseases; iii) more than 150 invited lectures since 2002 and more than 5500 citations (7800 citation-Google Scholar) since 1996. Dr. Lashuel has received several pre-doctoral and post-doctoral awards and fellowships and was the recipient of two prestigious awards given to young investigators; Human Science Frontiers young investigator research award and the European Research Council (ERC) starting independent researcher grant and the ERC proof of concept award (2013) These awards provide more than $2.5 Million to Dr. Lashuel to translate some of his ideas and projects into novel strategies for diagnosing and treating neurodegenerative diseases such as Alzheimers and Parkinsons disease. Dr. Lashuel has chaired and co-organized several international conferences and serves as an academic editor for PLoS ONE, an associate editor for frontiers of molecular neuroscience, member of the Editorial advisory board of ChemBioChem and ad hoc reviewer for several international scientific journals and funding agencies. Marco GrioniMarco Grioni est né à Milan (Italie). Après une thèse au Politecnico di Milano en 1982, il occupe des positions de recherche à Minneapolis (USA), Nijmegen (Pays Bas), Orsay (France) et Neuchâtel, où il devient Privat Docent en Physique du Solide en 1994. A l'EPFL depuis 1996, il est nommé professeur titulaire en 2005. Il enseigne la physique générale et dirige actuellement le Laboratoire de Spectroscopie Electronique de l'Institut de Physique.
Ses recherches portent sur les propriétés électroniques de nouveaux matériaux tels que les supraconducteurs à haute température, les métaux à basse dimension et les fermions lourds, qu'il étudie par la spectroscopie des photoélectrons (ARPES) à très haute résolution, par ultrafast time-resolved ARPES, et par d'autres techniques utilisant le rayonnement synchrotron. Auteur d'env. 220 publications, il participe activement au niveau suisse et européen au développement de nouveaux instruments. Entre 2003 et 2006 il a été chairman de l'organisation des utilisateurs du synchrotron européen de Grenoble (ESRF). De 2010 à 2017 il a été chairman du Scientific Advisory Committee du synchrotron national français SOLEIL.
Fabrizio CarboneBirth 20/04/1976
Master degree: University of Pavia "optoelectronic engineering". September 2001.
Reasearch scientist at Pirelli Labs, Milan Italy between September 2000 and August 2002.
PhD in condensed matter physics from the University of Geneva, prof. van der Marel gorup. January 2007
Post doc in physical chemistry at Caltech in prof. Zewail`s group. March 2007-April 2009
John Christopher PlummerÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL), Lausanne, Switzerland 1989-
Collaborateur Scientifique/Chargé de Cours (Lecturer) (1998-)
Privat Docent (1998)
Laboratoire de Technologie des Composites et Polymères (LTC) (2000-)
Laboratoire de Polymères (LP) (1998-2000)
UNIVERSITY OF MICHIGAN (UMICH), Ann Arbor, MI, USA 1995-1996
Visiting Scientist, Department of Materials Science and Engineering (DMSE)
UNIVERSITY OF CAMBRIDGE, Cambridge, UK 1986-1989
Research Assistant, Physics and Chemistry of Solids Group (PCS), Department of Physics
UNIVERSITY OF CAMBRIDGE, Cambridge, UK, Department of Materials 1986
PhD, "Flux Pinning in Type-II Superconductors"
UNIVERSITY OF CAMBRIDGE, Cambridge, UK, 1982
BA/MA Honours Degree in Natural Sciences
Awards
Prix R&R Haenny, 2007, DuPont Research Award, 2003, Commendation, British Polymer Group, Reading 1989
RECENT PUBLICATIONS
Ramier J, Da Costa N, Plummer CJG, Leterrier Y, Manson JAE, Eckert R, Gaudiana R, Cohesion and adhesion of nanoporous TiO2 coatings on titanium wires for photovoltaic applications, Thin solid films, 516, 1913 (2008).
Ramier J, Plummer CJG, Leterrier Y, Manson JAE, Eckert B, Gaudiana R, Mechanical integrity of dye-sensitized photovoltaic fibers, Renewable energy, 33, 314 (2008).
- Houphouet-Boigny C, Plummer CJG, Wakeman MD, Manson JAE, Hybrid glass fiber-reinforced thermoplastic nanocomposites, J. Thermoplast. Comp. Mater., 21, 103 (2008).
Ternat C, Ouali L, Sommer H, Fieber W, Velazco MI, Plummer CJG, Kreutzer G, Klok HA, Manson JAE, Herrmann, Investigation of the Release of Bioactive Volatiles from Amphiphilic Multiarm Star-Block Copolymers by Thermogravimetry and Dynamic Headspace Analysis, Macromolecules 41(19), 7079 (2008).
Ruggerone, R., Plummer, C.J.G., Negrete Herrera, N., Bourgeat-Lami, E., Månson, J-EA, Mechanical properties of highly filled latex-based polystyrene/laponite nanocomposites, Solid State Phenomena Vol. 151, 30 (2009).
Plummer, CJG, Dalle Vacche, S, Houphouët-Boigny, C, Michaud, V, Månson, JAE, Hybrid Glass Mat Reinforced Polypropylene-Montmorillonite Nanocomposites, Solid State Phenomena Vol. 151, 60 (2009).
Ruggerone, R., Plummer, C.J.G., Negrete Herrera, N., Bourgeat-Lami, E., Månson, J-EA, Highly filled polystyrenelaponite nanocomposites prepared by emulsion polymerization, European Polm. J. 45, 621 (2009).
Ruggerone, R., Plummer, C.J.G., Negrete Herrera, N., Bourgeat-Lami, E., Månson, J-EA, Fracture mechanisms in polystyrene/laponite nanocomposites prepared by emulsion polymerization, Engineering Fracture Mechanics 76, 2846 (2009)
Clausen P., Andreoni W., Curioni A., Hughs E., Plummer C.J.G. Adsorption of low-molecular-weight molecules on the surface of a sodium smectite clay: an ab initio study, Journal of Physical Chemistry C 113, 12293 (2009).
Clausen P., Andreoni W., Curioni A., Hughs E., Plummer C.J.G., Water adsorption on a sodium smectite clay surface: an ab initio study, Journal of Physical Chemistry C 113, 15218 (2009).
Molberg, M, Leterrier, Y., Plummer, C.J.G., Walder, C., Löwe, C., Opris, D.M., Nüesch, F.A., Bauer, S., Månson, J.-A.E., Frequency dependent dielectric and mechanical behaviour of elastomers for actuator applications, J. Appl. Phys. 106, 054112 (2009)
Clausen P., Signorelli M., Schreiber A., Hughes E., Plummer CJG, Fessas D., Schiraldi A., Månson E. J.-A., Equilibrium desorption isotherms of water, ethanol, ethyl acetate and toluene on a sodium smectite clay, Journal of Thermal Analysis and Calorimetry 98, 833 (2009)
Micusik, M., Bonnefond, A., Reyes, Y., Bogner, A., Chazeau, L., Plummer, C.J.G., Paulis, M., Leiza, J.R., Morphology of Polymer/Clay Latex Particles Synthesized by Miniemulsion Polymerization: Modeling and Experimental Results Macromol. React. Eng. 2010, 4, 432 (2010).
Houphouet-Boigny C., Plummer CJG, Vacche SD, Michaud V, Wakeman MD, Månson E. J.-A., Hybrid Glass Mat-reinforced Polypropylene-Montmorillonite Nanocomposites, J. Comp. Mater. 44, 1975 (2010).
Delabarde, C., Plummer C.J.G., Bourban, P.-E., Månson E. J.-A., Solidification behavior of PLLA/nHA nanocomposites, Comp. Sci. & Tech. 70, 1813 (2010).
Plummer C.J.G., Ruggerone R., Negrete-Herrera N., Bourgeat-Lami E., Månson J.-A.E., Small Strain Mechanical Properties of Latex-Based Nanocomposite Films, Macromol. Symp. 294, 1 (2010).
Dalle Vacche, S., Plummer C.J.G., Houphouet-Boigny C., Månson E. J.-A., Morphology and mechanical properties of isotactic polypropylene glass mat thermoplastic composites modified with organophilic montmorillonite, J Mater Sci 46, 2112 (2011). Marcel DrabbelsD'origine néerlandaise, Marcel Drabbels est né à Venray en 1966. Il a fait ses études en physique expérimentale à l'Université de Nijmegen et a obtenu son titre de docteur en 1993 dans cette même université. Il a ensuite poursuivi des études postdoctorales à l'Université de Californie à Santa Barbara où il a effectué des recherches dans le domaine de la dynamique des molécules dans des états vibrationnels hautement excités et a développé une nouvelle technique de détection pour l'étude de la photodissociation des molécules. En 1996, il est retourné aux Pays-Bas pour joindre le FOM Institute for Atomic and Molecular Physics à Amsterdam où il a mis au point un nouveau type de " streak cameras " pour linfrarouge. En 1997, M. Drabbels a été nommé membre de lAcadémie Royale Hollandaise des Sciences et a poursuivi sa carrière à lUniversité Libre dAmsterdam. Il y a étudié la dynamique des collisions de molécules et a initié des expériences de photodissociation en utilisant des lasers ultrarapides. Il a été nommé Maître d'Enseignement et Recherche (MER) à partir du 1er octobre 1998 au Département de chimie de l'EPFL. Il se consacre à l'étude de la dynamique nanoscopique. En mars 2021, il est promu professeur titulaire.
