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The epithelial-to-mesenchymal transition (EMT) is a developmental program frequently reactivated in cancer. It plays an important role in several aspects of tumor progression, particularly in the acquisition of invasive capacities facilitating metastasis. ...
Evolution can be described as the change of allele frequencies over time. Four forces - mutation, migration, genetic drift, and selection, drive this change. The aim of my thesis was to accurately estimate and differentiate the parameters governing each of ...
During embryonic development, fields of progenitor cells form complex structures through dynamic interactions with external signaling molecules. How complex signaling inputs are integrated to yield appropriate gene expression responses is poorly understood ...
Robotic agents that are accepted by animals as conspecifics are very powerful tools in behavioral biology because of the ways they help in studying social interactions in gregarious animals. In recent years, we have developed a biomimetic robotic fish lure ...
Capturing students' behavioral patterns through analysis of sequential interaction logs, is an important task in educational data mining to enable more effective personalized support during the learning process. This study aims at discovery and temporal an ...
Proliferative kidney disease (PKD) is a high-mortality pathology that critically affects freshwater salmonid populations. Infection is caused by the endoparasitic myxozoan Tetracapsuloides bryosalmonae, which exploits freshwater bryozoans as primary hosts. ...
Cation ordering is expected to influence the properties of oxides in the ZrO2−YTaO4 system, but the ordering patterns and their relative energies are not well understood. This work investigates the stability of zirconium-yttrium-tantalum orderings over the ...
Chiral active particles (or self-propelled circle swimmers) feature a rich collective behavior, comprising rotating macro-clusters and micro-flock patterns which consist of phase-synchronized rotating clusters with a characteristic self-limited size. These ...
Collinear regulation of Hox genes in space and time has been an outstanding question ever since the initial work of Ed Lewis in 1978. Here we discuss recent advances in our understanding of this phenomenon in relation to novel concepts associated with larg ...
Drosophila leg morphogenesis occurs under the control of a relatively well-known genetic cascade, which mobilizes both cell signaling pathways and tissue-specific transcription factors. However, their cross-regulatory interactions, deployed to refine leg p ...