Graham KnottGraham Knott received his degree in physiology from the University of Southampton, UK, in 1990, and his PhD in neuroscience from the University of Tasmania, Australia, in 1995. He moved to the University of Lausanne in Switzerland in 1999 where he researched the plasticity of neuronal connectivity in the adult brain, developing correlative light and electron microscopy methods for the analysis of in vivo imaged neurons. In 2006 Graham joined the Ecole Polytechnique Fédérale de Lausanne, establishing the Bio Electron Microscopy Facility and has continued his research interests in brain plasticity and 3D electron microscopy.
Ursula RöthlisbergerU. Röthlisberger was born in Solothurn (Switzerland). In 1988 she made her diploma in Physical Chemistry in the group of Prof. Ernst Schumacher at the University of Berne (Switzerland). Her Ph.D. thesis was done in collaboration with Dr. Wanda Andreoni at the IBM Zurich Research Laboratory in Rüschlikon. After finishing her Ph.D in 1991 she spent some time as a postdoctoral research assistant at the IBM Research Lab. From 1992-1995 she was a postdoctoral research assistant in the group of Prof. Michael L. Klein at the University of Pennsylvania in Philadelphia (USA). In 1994 she was awarded an advanced researcher fellowship (Profil 2) from the Swiss National Science Foundation. Before starting her Profile 2-fellowship she spent another year as postdoctoral research assistant in the group of Prof. Michele Parrinello at the Max-Planck-Institute for Solid State Physics in Stuttgart, Germany. In 1996 she moved as Profile 2-fellow to the ETH in Zurich, hosted by the group of Prof. Wilfred F. van Gunsteren. In 1997 she became Assistant Professor of Computer-Aided Inorganic Chemistry at the ETH Zurich.
Carl PetersenCarl Petersen studied physics as a bachelor student in Oxford (1989-1992). During his PhD studies under the supervision of Prof. Sir Michael Berridge in Cambridge (1992-1996), he investigated cellular and molecular mechanisms of calcium signalling. In his first postdoctoral period (1996-1998), he joined the laboratory of Prof. Roger Nicoll at the University of California San Francisco (UCSF) to investigate synaptic transmission and plasticity in the hippocampus. During a second postdoctoral period, in the laboratory of Prof. Bert Sakmann at the Max Planck Institute for Medical Research in Heidelberg (1999-2003), he began working on the primary somatosensory barrel cortex, investigating cortical circuits and sensory processing. Carl Petersen joined the Brain Mind Institute of the Faculty of Life Sciences at the Ecole Polytechnique Federale de Lausanne (EPFL) in 2003, setting up the Laboratory of Sensory Processing to investigate the functional operation of neuronal circuits in awake mice during quantified behavior. In 2019, Carl Petersen became the Director of the EPFL Brain Mind Institute, with the goal to promote quantitative multidisciplinary research into neural structure, function, dysfunction, computation and therapy through technological advances.
Hilal Lashuel2012-2013 Visiting Professor, Standford University. Stanford School of Medicine
2011- Associate Professor of Life Sciences-Brain Mind Institute-EPFL
Dir. Laboratory of Chemical Biology of Neurodegeneration
2005-2011 Assistant Professor of Life Sciences-Brain Mind Institute-EPFL
Dir. Laboratory of Molecular Neurobiology and Neuroproteomics
2005-2008 Director- EPFL Proteomic Core Facility
2002-2004 Instructor of Neurology- Harvard Medical School and Brigham and Women's
Hospital
2001-2002 Sabbatical Fellow- Laboratory for Drug Discovery in Neurodegeneration
Harvard Medical School,
2001-2002 Post-doctoral Fellow- Center for Neurologic Diseases
Harvard Medical School and Brigham and Women's Hospital
Advisor- Prof. Peter T. Lansbury
2000-2001 Research Scientist, The Picower Institute for Medical Research, Great Neck
New York
1994-2000 PhD Student; Texas A&M University and the Scripps Research Institute
Advisor- Prof. Jeffery W. Kelly
1990-1994 B.S. City University of New York, Brooklyn College
Dr. Hilal A. Lashuel received his B.Sc. degree in chemistry from the City University of New York in 1994 and completed his doctoral studies at Texas A&M University and the Scripps Research Institute in 2000. After obtaining his doctoral degree, he became a research fellow at the Picower Institute for Medical Research in Long Island New York. In 2001, he moved to Harvard Medical School and the Brigham and Women's Hospital as a research fellow in the Center for Neurologic Diseases and was later promoted to an instructor in neurology at Harvard Medical School. During his tenure (2001-2004) at Harvard Medical School his work focused on understanding the mechanisms of protein misfolding and fibrillogenesis and the role of these processes in the pathogenesis of Parkinson's and Alzheimer's disease. In 2005 Dr. Lashuel moved Switzerland to join the Brain Mind Institute at the Swiss Federal Institute of Technology Lausanne as a tenure-track assistant professor in neurosciences. Currently, Dr. Lashuel is an associate professor of life sciences and the director of the laboratory of molecular and chemical biology of neurodegeneration. (http://lashuel-lab.epfl.ch/).
Research efforts in the Lashuels laboratory focus on understanding the molecular mechanisms of neurodegeneration and developing novel strategies to diagnose and treat neurodegenerative diseases such as Alzheimers and Parkinsons disease. Research in the Lashuel lab is funded by several international funding agencies and foundations, including the Swiss National Science Foundation, European FP7 program (Marie Curie and ERC grants), Human Science Frontiers, Strauss Foundation, Cure the Huntingtons disease foundation and Michael J Fox foundation and is supported by collaborations with pharmaceutical and biotech companies (http://lashuel-lab.epfl.ch/page-50538-en.html), Nestle, Merck-Serono, AC Immune and Johnson and Johnson.
Dr. Lashuels research has resulted in the characterization of novel quaternary structure intermediates on the amyloid pathway, identification of potential therapeutic targets, and new hypotheses concerning the mechanisms of pathogenesis in Alzheimers disease, Parkinsons disease and related disorders. Dr. Lashuel scientific contribution to this field includes i) more than100 publications in major peer reviewed journals including Nature journals, Cell, PNAS, JBC, J. Neuroscience JACS, and Angewandtie Chemie; ii) three patents on novel strategies for preventing protein aggregation and treating autoimmune and inflammatory diseases; iii) more than 150 invited lectures since 2002 and more than 5500 citations (7800 citation-Google Scholar) since 1996. Dr. Lashuel has received several pre-doctoral and post-doctoral awards and fellowships and was the recipient of two prestigious awards given to young investigators; Human Science Frontiers young investigator research award and the European Research Council (ERC) starting independent researcher grant and the ERC proof of concept award (2013) These awards provide more than $2.5 Million to Dr. Lashuel to translate some of his ideas and projects into novel strategies for diagnosing and treating neurodegenerative diseases such as Alzheimers and Parkinsons disease. Dr. Lashuel has chaired and co-organized several international conferences and serves as an academic editor for PLoS ONE, an associate editor for frontiers of molecular neuroscience, member of the Editorial advisory board of ChemBioChem and ad hoc reviewer for several international scientific journals and funding agencies. Paul Joseph DysonPaul Dyson rejoignit l’EPFL en 2002 à la tête du Laboratoire de chimie organométallique et médicinale de l’Institut des sciences et ingénierie chimiques, dont il en assuma ensuite la direction entre 2008 et 2016.
Le prof. Dyson a été récompensé par de nombreux prix dont le Prix Werner de la Société Suisse de Chimie en 2004, le Prix pour les réalisations exceptionnelles en chimie bio organométallique en 2010, la Médaille du Centenaire de la naissance de Luigi Sacconi (2011) de la Société Italienne de Chimie, le Prix de Chimie bio-inorganique de la Royal Society of Chemistry en 2015, le Prix européen pour une chimie durable de la Société Européenne de Chimie en 2018 et le Prix pour la chimie verte de la Royal Society of Chemistry en 2020.
Le prof. Dyson est également mentionné dans la liste établie par Clarivate des chercheurs les plus cités (Clarivate Highly Cited Researcher), avec un H-index >110 (Web of Science et Google Scholar). Paul Dyson a été élu membre de la Royal Société de Chimie en 2010, membre de l’Académie Européenne des Sciences en 2019 et membre à vie de l’Association Américaine pour l’Avancement de la Science en 2020. Au cours des dernières années il s’est vu décerner le titre de Professeurs Hôte par l’Université de Bourgogne, l’Université de Pierre et Marie Curie, l’Université de Vienne, l’Université de Rome Tor Vergara, l'Ecole Nationale Supérieure de chimie de Paris (Chimie ParisTech) et par l’Université de Shangai Jiao Tong.
De 2016 à 2021 il était membre du conseil de la recherche de la division de mathématique, sciences naturelles et de l’ingénieur du Fonds National Suisse. En 2021, il a été nommé doyen de la Faculté des Sciences de Base.
Kamiar AminianKamiar Aminian received the M.S. degree in electrical engineering in 1982, the Ph.D degree in biomedical engineering in 1989 and the Postgraduate degree on technical computing in 1993 from Ecole Polytechnique Fédérale de Lausanne (EPFL). He was assistant professor (1994-1996) with Sharif University of Technology (Tehran). He joint EPFL in 1996 where he is currently Professor of medical instrumentation and the director of the Laboratory of Movement Analysis and Measurement in the Institute of Bioengineering of EPFL. His research interests include methodologies for human movement monitoring and analysis in real world conditions mainly based on wearable technologies and inertial sensors with emphasis on gait, physical activity and sport. His research aims to perform outcome evaluation in orthopaedics, to improve motor function and intervention programs in aging and patients with movement disorders and pain, and to identify metrics of performance in sport science.
Kamiar Aminian is a member of the International Society of Posture and Gait Research, the Institute of Electrical and Electronics Engineers, the European Society of Movement Analysis in Adults and Children, the Prevention of fall Network Europe, the Intentional Society of Biomechanics and the President of the 3D analysis of the human movement group. He is author or co-author of more than 450 scientific papers published in reviewed journals and presented at international conferences and holds 10 patents related to medical devices.
Full CV
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