Publications associées à Toxine

Synthesis of diphenoxyadamantane alkylamines with pharmacological interest

In this work, the synthesis and the pharmacological evaluation of diphenoxyadamantane alkylamines Ia-f and IIa-f is described. The new diphenoxy-substituted adamantanes share structural features present in trypanocidal and antitubercular agents. 1-Methylpi ...

PERGAMON-ELSEVIER SCIENCE LTD2019

Safely Managed Hygiene: A Risk-Based Assessment of Handwashing Water Quality

Matthew Eric Verbyla, Timothy R. Julian

Sustainable Development Goal (SDG) Indicator 6.2.1 requires household handwashing facilities to have soap and water, but there are no guidelines for handwashing water quality. In contrast, drinking water quality guidelines are defined: water must be "free ...

AMER CHEMICAL SOC2019

Biogenesis of the mitochondrial DNA inheritance machinery in the mitochondrial outer membrane of Trypanosoma brucei

Mathilde Stéphanie Willemin, André Schneider

Mitochondria cannot form de novo but require mechanisms that mediate their inheritance to daughter cells. The parasitic protozoan Trypanosoma brucei has a single mitochondrion with a single-unit genome that is physically connected across the two mitochondr ...

2017

Genomic diversity and disease prevalence in Ugandan cattle

Stéphane Joost, Sylvie Stucki, Elia Vajana, Pierre Taberlet

Ugandan cattle are represented by three main types: the long-horned Ankole, the short-horned zebu, and the Ankole-zebu crosses called “Nganda”. In the course of the EU-funded project Nextgen, Ugandan cattle have been extensively sampled over the whole coun ...

2015

Infection Dynamics and Immune Response in a Newly Described Drosophila-Trypanosomatid Association

Bruno Lemaitre, Anna Dostalova

Trypanosomatid parasites are significant causes of human disease and are ubiquitous in insects. Despite the importance of Drosophila melanogaster as a model of infection and immunity and a long awareness that trypanosomatid infection is common in the genus ...

American Society for Microbiology2015

Metabolic Needs and Capabilities of Toxoplasma gondii through Combined Computational and Experimental Analysis

Vassily Hatzimanikatis, Stepan Tymoshenko, Rebecca Oppenheim, Jens Nielsen, Dominique Soldati-Favre

Toxoplasma gondii is a human pathogen prevalent worldwide that poses a challenging and unmet need for novel treatment of toxoplasmosis. Using a semi-automated reconstruction algorithm, we reconstructed a genome-scale metabolic model, ToxoNet1. The reconstr ...

Public Library Science2015

Flagellar membranes are rich in raft-forming phospholipids

Adrian Schmid

The observation that the membranes of flagella are enriched in sterols and sphingolipids has led to the hypothesis that flagella might be enriched in raft-forming lipids. However, a detailed lipidomic analysis of flagellar membranes is not available. Novel ...

Company Of Biologists Ltd2015

The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system

Denis Duboule

Snakes are limbless predators, and many species use venom to help overpower relatively large, agile prey. Snake venoms are complex protein mixtures encoded by several multilocus gene families that function synergistically to cause incapacitation. To examin ...

National Academy of Sciences2013

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Toxine

Synthesis of diphenoxyadamantane alkylamines with pharmacological interest

Safely Managed Hygiene: A Risk-Based Assessment of Handwashing Water Quality

Biogenesis of the mitochondrial DNA inheritance machinery in the mitochondrial outer membrane of Trypanosoma brucei

Genomic diversity and disease prevalence in Ugandan cattle

Infection Dynamics and Immune Response in a Newly Described Drosophila-Trypanosomatid Association

Metabolic Needs and Capabilities of Toxoplasma gondii through Combined Computational and Experimental Analysis

Reconstruction and systems analysis of metabolism in apicomplexan parasites Toxoplasma gondii and Plasmodium falciparum

Flagellar membranes are rich in raft-forming phospholipids

The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system

The C-type Lectin Receptors Dectin-1, MR, and SIGNR3 Contribute Both Positively and Negatively to the Macrophage Response to Leishmania infantum

Graph Chatbot

Chattez avec Graph Search

Biogenesis of the mitochondrial DNA inheritance machinery in the mitochondrial outer membrane of Trypanosoma brucei

Infection Dynamics and Immune Response in a Newly Described Drosophila-Trypanosomatid Association

Reconstruction and systems analysis of metabolism in apicomplexan parasites Toxoplasma gondii and Plasmodium falciparum

Genomic diversity and disease prevalence in Ugandan cattle

Flagellar membranes are rich in raft-forming phospholipids

The C-type Lectin Receptors Dectin-1, MR, and SIGNR3 Contribute Both Positively and Negatively to the Macrophage Response to Leishmania infantum

Metabolic Needs and Capabilities of Toxoplasma gondii through Combined Computational and Experimental Analysis

The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system

Synthesis of diphenoxyadamantane alkylamines with pharmacological interest

Safely Managed Hygiene: A Risk-Based Assessment of Handwashing Water Quality