Concept

Érythromycine

Publications associées (7)

Unravelling the collateral damage of antibiotics on gut bacteria

Antibiotics are used to fight pathogens but also target commensal bacteria, disturbing the composition of gut microbiota and causing dysbiosis and disease1. Despite this well-known collateral damage, the activity spectrum of different antibiotic classes on ...

2021

Bioaccumulation of antibiotics in wild freshwater invertebrates

Luiz Felippe De Alencastro, Marc Chevreuil

Occurrence and bioaccumulation of 20 antibiotics, including fluoroquinolones (FQs), sulfonamids (SAs), macrolids (MLs), tetracyclins (TCs),diaminopyrimidins (DPs) and nitro-imidazols (NIs) in an amphipod crustacean (Gammarus pulex) inhabiting in the small ...

2017

Optimization of drug combinations using Feedback System Control

Paul Joseph Dyson, Hubert van den Bergh, Patrycja Nowak-Sliwinska

We describe a protocol for the discovery of synergistic drug combinations for the treatment of disease. Synergistic drug combinations lead to the use of drugs at lower doses, which reduces side effects and can potentially lead to reduced drug resistance, w ...

Nature Publishing Group2016

Phage Selection of Bicyclic Peptides and High-Throughput Screening of Chemical Compounds for the Identification of Novel Inhibitors of the Notch Pathway

Notch signaling is a highly conserved developmental pathway that plays important roles in the regulation of cellular processes including cell fate decisions and stem cell maintenance. A tight regulation of the Notch cascade ensures proper tissue homeostasi ...

EPFL2015

Methodology to account for uncertainties and tradeoffs in pharmaceutical environmental hazard assessment

David Andrew Barry, Luca Rossi, Sylvain Coutu

Many pharmaceutical products find their way into receiving waters, giving rise to concerns regarding their environmental impact. A procedure was proposed that enables ranking of the hazard to aquatic species and human health due to such products. In the pr ...

Elsevier2012

Secondary Metabolites from Cyanobacteria: Complex Structures and Powerful Bioactivities

Cyril Portmann, Karl Gademann

This review presents natural products from cyanobacteria. Several classes of secondary metabolites are highlighted. Toxic metabolites from these prokaryotic photosynthetic organisms include compounds such as microcystin, anatoxin and saxitoxin, which displ ...

2008

Use of reaction calorimetry to monitor and control microbial cultures producing industrially relevant secondary metabolites

Urs von Stockar, Ian William Marison

Bench-scale heat flux calorimetry is applied to monitor complex microbial systems producing secondary metabolites and having a rheol. complex behavior. With such systems, biol. metabolic activity can only be measured accurately if calorimetry is improved b ...

1998

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