Concept

Acide aminé cétoformateur

Publications associées (81)

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Fragmentation of doubly charged biomolecules, uracil and amino acids, has been investigated using different ab inito Molecular Dynamics Methods. Time-Dependent Density Functional Theory Molecular Dynamics give a description of the non-adiabatic effects, th ...

Iop Publishing Ltd2014

The cyclic AMP-dependent transcriptional regulator GlxR from Corynebacterium glutamicum is a member of the super-family of CRP/FNR (cyclic AMP receptor protein/fumarate and nitrate reduction regulator) transcriptional regulators that play central roles in ...

Public Library of Science2014

Surface Modification of Polyimide Thin Films for Peripheral Invasive Neural Interfaces

Silvestro Micera

Despite recognized as one key component for establishing a functional electrical connection with nerves, neural invasive peripheral interfaces are still not optimal for long-term applications in humans. An improvement in the field of biocompatible and nont ...

Asme2013

A quantitative telomeric chromatin isolation protocol identifies different telomeric states

Joachim Lingner, Romain Hamelin, Florence Armand, Diego Chiappe, Marc Moniatte, Eric Aeby, Larissa Grolimund

Telomere composition changes during tumourigenesis, aging and in telomere syndromes in a poorly defined manner. Here we develop a quantitative telomeric chromatin isolation protocol (QTIP) for human cells, in which chromatin is cross-linked, immunopurified ...

Nature Publishing Group2013

Multiple Isomers and Protonation Sites of the Phenylalanine/Serine Dimer

Thomas Rizzo, Ulrich Lorenz

Our investigation of the phenylalanine/serine (Phe/Ser) protonated dimer suggests that the intermolecular interaction between the two amino acids is more complex than could have been anticipated from previous studies of similar systems. Isomer-specific inf ...

2012

Glycopeptide dendrimers: Tuning carbohydrate-lectin interactions with amino acids

Ronan Euzen, Jean-Louis Reymond

Glycodendrimers, such as glycoclusters and glycopolymers, are known to be very useful molecules to probe carbohydrate-lectin interactions. Herein, new second generation glycopeptide dendrimers (G2a-f) presenting a L-lysin-based (Lys) tetraantennary scaffol ...

Royal Society of Chemistry2011

Visualization of proprotein convertase activity in living cells and tissues

Daniel Constam

The invention relates to a system for detecting the presence of a convertase cleaving activity, the system comprising a molecule comprising a proteolytic cleavage site with the amino acid sequence -R-X1-X2-R-, wherein R represents the amino acid arginine, ...

2011

Neutron Reflectivity Study on the Postpolymerization Modification of Poly(2-hydroxyethyl methacrylate) Brushes

Harm-Anton Klok, Juan Pablo Hinestrosa Salazar

Postpolymerization modification reactions are widely employed to prepare functional polymer brushes. Relatively little is known, however, about the distribution of functional groups in such postmodified brushes. Using neutron reflectometry and UV-vis spect ...

American Chemical Society2011

Pseudomonas entomophila is an entomopathogenic bacterium that is able to infect and kill Drosophila melanogaster upon ingestion. Its genome sequence suggests that it is a versatile soil bacterium closely related to Pseudomonas putida. The GacS/GacA two-com ...

2010

Synthetic Studies on (-)-Lemonomycin: An Efficient Asymmetric Synthesis of Lemonomycinone Amide

Jieping Zhu

Asym. synthesis of lemonomycinone amide was accomplished from readily accessible starting materials. Enantioselective alkylation of N-(diphenylmethylene)glycine tert-Bu ester by 5-tert-butyldimethylsilyloxy-2,4-dimethoxy-3-methylbenzyl bromide in the prese ...

2009

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