Publications associées à Lipoxin

Bcl-xL targeting eliminates ageing tumor-promoting neutrophils and inhibits lung tumor growth

Freddy Radtke, Nadine Fournier, Etienne Meylan, Justine Pascual, Amber Dawn Bowler, Anita Bodac, Vincent Roh

Elevated peripheral blood and tumor-infiltrating neutrophils are often associated with a poor patient prognosis. However, therapeutic strategies to target these cells are difficult to implement due to the life-threatening risk of neutropenia. In a genetica ...

Springernature2024

Boosted Pro-Inflammatory Activity in Human PBMCs by Lipopolysaccharide and SARS-CoV-2 Spike Protein Is Regulated by alpha-1 Antitrypsin

Florian Maria Wurm, Divor Kiseljak

For the treatment of severe COVID-19, supplementation with human plasma-purified alpha-1 antitrypsin (AAT) to patients is currently considered. AAT inhibits host proteases that facilitate viral entry and possesses broad anti-inflammatory and immunomodulato ...

MDPI2021

Immune serum-activated human macrophages coordinate with eosinophils to immobilize Ascaris suum larvae

Beatrice Volpe, Julia Esser-von Bieren, Tiffany Babette Angélique Bouchery, Kathleen Shah

Helminth infection represents a major health problem causing approximately 5 million disability-adjusted life years worldwide. Concerns that repeated anti-helminthic treatment may lead to drug resistance render it important that vaccines are developed but ...

WILEY2020

Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes

Nahal Mansouri, Sina Nassiri

Mesenchymal stromal/stem cell (MSC) therapy has shown promise in experimental models of idiopathic pulmonary fibrosis (IPF). The aim of this study was to test the therapeutic effects of extracellular vesicles produced by human BM MSCs (MEx) in a bleomycin- ...

AMER SOC CLINICAL INVESTIGATION INC2019

Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles

Michele De Palma, Romain Hamelin, Bruno Torchia, Chiara Cianciaruso, Sina Nassiri, Tim Beltraminelli

Extracellular vesicles (EVs), including exosomes, modulate multiple aspects of cancer biology. Tumor-associated macrophages (TAMs) secrete EVs, but their molecular features and functions are poorly characterized. Here, we report methodology for the enrichm ...

2019

Exploiting lymphatic vessels for immunomodulation: Rationale, opportunities, and challenges

Melody Swartz, Lambert Charles François Potin

Lymphatic vessels are the primary route of communication from peripheral tissues to the immune system; as such, they represent an important component of local immunity. In addition to their transport functions, new immunomodulatory roles for lymphatic vess ...

Elsevier Science Bv2017

Alamandine abrogates neutrophil degranulation in atherosclerotic mice

Nikolaos Stergiopoulos, Rodrigo Araujo Fraga Da Silva

Background Neutrophil-mediated inflammation was recently identified as an active contributor to athero-progression. Therapeutic strategies inhibiting neutrophil degranulation or recruitment were hypothesized to positively impact on plaque vulnerability. In ...

Wiley-Blackwell2017

Ophthalmic contact lens with a compressible affinity matrix

Philippe Renaud, Thomas Michael Braschler, Amélie Barbara Hildegarde Béduer

The invention relates to a contact lens for use in the treatment of ocular inflammatory pathologies. The contact lens comprises a soft porous material coupled, in certain embodiments, with detoxifying agents. Said material and/or agents contact and neutral ...

2016

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Lipoxin

Bcl-xL targeting eliminates ageing tumor-promoting neutrophils and inhibits lung tumor growth

Boosted Pro-Inflammatory Activity in Human PBMCs by Lipopolysaccharide and SARS-CoV-2 Spike Protein Is Regulated by alpha-1 Antitrypsin

Emodin Inhibits Inflammation, Carcinogenesis, and Cancer Progression in the AOM/DSS Model of Colitis-Associated Intestinal Tumorigenesis

Immune serum-activated human macrophages coordinate with eosinophils to immobilize Ascaris suum larvae

Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes

Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles

Exploiting lymphatic vessels for immunomodulation: Rationale, opportunities, and challenges

Alamandine abrogates neutrophil degranulation in atherosclerotic mice

Proteome-Wide Effect of 17-beta-Estradiol and Lipoxin A(4) in an Endometriotic Epithelial Cell Line

Ophthalmic contact lens with a compressible affinity matrix

Graph Chatbot

Chattez avec Graph Search

Boosted Pro-Inflammatory Activity in Human PBMCs by Lipopolysaccharide and SARS-CoV-2 Spike Protein Is Regulated by alpha-1 Antitrypsin

Immune serum-activated human macrophages coordinate with eosinophils to immobilize Ascaris suum larvae

Bcl-xL targeting eliminates ageing tumor-promoting neutrophils and inhibits lung tumor growth

Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes

Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles

Emodin Inhibits Inflammation, Carcinogenesis, and Cancer Progression in the AOM/DSS Model of Colitis-Associated Intestinal Tumorigenesis

Proteome-Wide Effect of 17-beta-Estradiol and Lipoxin A(4) in an Endometriotic Epithelial Cell Line

Alamandine abrogates neutrophil degranulation in atherosclerotic mice

Ophthalmic contact lens with a compressible affinity matrix

Exploiting lymphatic vessels for immunomodulation: Rationale, opportunities, and challenges