Publications associées à Somite

A CTCF-dependent mechanism underlies the Hox timer relation to a segmented body plan

During gastrulation, Hox genes are activated in a timesequence that follows the order of the genes along their clusters. This property, which is observed in all animals that develop following a progressive rostral-to-caudal morphogenesis, is associated wit ...

Current Biology Ltd2024

RibSeg v2: A Large-Scale Benchmark for Rib Labeling and Anatomical Centerline Extraction

Jiancheng Yang, Jason Ken Adhinarta, Ming Li

Automatic rib labeling and anatomical centerline extraction are common prerequisites for various clinical applications. Prior studies either use in-house datasets that are inaccessible to communities, or focus on rib segmentation that neglects the clinical ...

Piscataway2024

Reaction wavefront theory of notochord segment patterning

Andrew Charles Oates

The vertebrate axis is segmented into repetitive structures, the vertebrae. In fish, these segmented structures are thought to form from the paraxial mesoderm and the adjacent notochord. Recent work revealed an autonomous patterning mechanism in the zebraf ...

FRONTIERS MEDIA SA2022

Preparation of Single-Somite Explants from Zebrafish Embryos

Andrew Charles Oates, Sundar Ram Naganathan

The body axis of vertebrate embryos is periodically subdivided into 3D multicellular units called somites. While genetic oscillations and molecular prepatterns determine the initial length-scale of somites, mechanical processes have been implicated in sett ...

JOURNAL OF VISUALIZED EXPERIMENTS2022

Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence

Cathrin Brisken, Giovanna Ambrosini, Georgios Sflomos, Yueyun Zhang, Hazel Margaret Quinn, Kelly Spry Maggs, Patrik Aouad, Fabio De Martino, Céline Marie Victoria Stibolt

More than 70% of human breast cancers (BCs) are estrogen receptor α-positive (ER+). A clinical challenge of ER+ BC is that they can recur decades after initial treatments. Mechanisms governing latent disease remain elusive due to lack of adequate in vivo m ...

2022

A Tead1-Apelin axis directs paracrine communication from myogenic to endothelial cells in skeletal muscle

Bart Deplancke, Julie Marie Russeil, Sonia Karaz, Maria Deak, Umji Lee, Benjamin D. Cosgrove

Apelin (Apln) is a myokine that regulates skeletal muscle plasticity and meta-bolism and declines during aging. Through a yeast one-hybrid transcription factor binding screen, we identified the TEA domain transcription factor 1 (Tead1) as a novel regulator ...

CELL PRESS2022

Theory of time delayed genetic oscillations with external noisy regulation

Andrew Charles Oates, Laurel Ann Rohde, Jose Negrete Jr

Video Abstract Video Abstract: Theory of time delayed genetic oscillations with external noisy regulation We present a general theory of noisy genetic oscillators with externally regulated production rate and multiplicative noise. The observables that char ...

IOP PUBLISHING LTD2021

Patterning and mechanics of somite boundaries in zebrafish embryos

Andrew Charles Oates, Sundar Ram Naganathan

The body axis of vertebrates is subdivided into repetitive compartments called somites, which give rise primarily to the segmented architecture of the musculoskeletal system in the adult body. Somites form in a sequential and rhythmic manner in embryos and ...

2020

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Somite

A CTCF-dependent mechanism underlies the Hox timer relation to a segmented body plan

RibSeg v2: A Large-Scale Benchmark for Rib Labeling and Anatomical Centerline Extraction

How are cells instructed to form somite boundaries by the zebrafish segmentation clock?

Hunting for the wavefront: investigation of somite boundary positioning in zebrafish

Reaction wavefront theory of notochord segment patterning

Preparation of Single-Somite Explants from Zebrafish Embryos

Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence

A Tead1-Apelin axis directs paracrine communication from myogenic to endothelial cells in skeletal muscle

Theory of time delayed genetic oscillations with external noisy regulation

Patterning and mechanics of somite boundaries in zebrafish embryos

Graph Chatbot

Chattez avec Graph Search

Reaction wavefront theory of notochord segment patterning

How are cells instructed to form somite boundaries by the zebrafish segmentation clock?

Patterning and mechanics of somite boundaries in zebrafish embryos

Preparation of Single-Somite Explants from Zebrafish Embryos

A CTCF-dependent mechanism underlies the Hox timer relation to a segmented body plan

Hunting for the wavefront: investigation of somite boundary positioning in zebrafish

RibSeg v2: A Large-Scale Benchmark for Rib Labeling and Anatomical Centerline Extraction

Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence

A Tead1-Apelin axis directs paracrine communication from myogenic to endothelial cells in skeletal muscle

Theory of time delayed genetic oscillations with external noisy regulation