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In vitro endothelial cell organization into capillaries is a long standing challenge of tissue engineering. We recently showed the utility of low level interstitial flow in guiding the organization of endothelial cells through a 3-D fibrin matrix-containin ...
The early requirements of an IT system should be aligned with the organization’s business imperatives. To understand these imperatives it is necessary to understand the organization’s position within its environment. SEAM for Business is a method designed ...
To align an IT system with an organization’s needs, it is necessary to understand the organization’s position within its environment a well as its internals. In SEAM for Enterprise Architecture the organization is considered as a hierarchy of systems that ...
Although all bilaterian animals have a related set of Hox genes, the genomic organization of this gene complement comes in different flavors. In some unrelated species, Hox genes are clustered; in others, they are not. This indicates that the bilaterian an ...
Enterprise Architecture (EA) projects require analyzing and designing across the whole enterprise and its environment. Enterprise architects, therefore, frequently develop enterprise models that span from the markets in which the organization operates down ...
The mechanisms by which global structure is extracted from local orientation information are not well understood. Sensitivity to global structure can be investigated using coherence thresholds for detection of global forms of varying complexity, such as pa ...
Package universes is a component-distribution architecture based on explicitly managing the set of components visible at assembly time. The architecture is usable as is for a number of common organizations and software-engineering processes. Also, by provi ...
The present article aims at assessing the possibility for urban areas to coordinate local policies of urban development and public transportation and at explaining the differences in this achievement between urban regions. In order to do so, the study draw ...
Knowledge acquisition activities occurring may be just as critical to firm survival as pre-existing knowledge and experience, because knowledge acquisition activities enable the augmentation of existing knowledge and the exploration and pursuit of new stra ...
Exploratory activities seem to be intrinsicallyrewarding for children and crucial for their cognitive development. Can a machine be endowed with such an intrinsic motivation system? This is the question we study in this paper, presenting a number of comput ...