Concept
Sidérophore
Publications associées (38)
Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome
Background: The gut microbiome and iron status are known to play a role in the pathophysiology of nonalcoholic fatty liver disease (NAFLD), although their complex interaction remains unclear. Results: Here, we applied an integrative systems medicine approa ...
BMC2021Functional and structural characterization of Serratia marcescens ExbB: determinants of the interaction with HasB/TonB
ExbBD is part of a cytoplasmic membrane molecular motor driven by the proton-motive force. It belongs to the larger family of motors involved in nutriment import across the outer membrane of Gram-negative bacteria (ExbBD), flagellar rotation (MotAB) or lat ...
2021The molecular treasure box of environmental Vibrio cholerae strains
Cholera pandemics have been affecting humankind for centuries and are still considered a major public health problem, especially in regions around the world with poor access to clean water and sanitation. Cholera pandemics are caused by a specific lineage ...
EPFL2021Iron sequestration by transferrin 1 mediates nutritional immunity in Drosophila melanogaster
Bruno Lemaitre, Jean Philippe Boquete, Igor Iatsenko, Alice Marra, Jasquelin Peña
Iron sequestration is a recognized innate immune mechanism against invading pathogens mediated by iron-binding proteins called transferrins. Despite many studies on antimicrobial activity of transferrins in vitro, their specific in vivo functions are poorl ...
NATL ACAD SCIENCES2020