Concept

Cultured neuronal network

Publications associées (52)

A hybrid bio-organic interface for neuronal photo-activation

Interfacing artificial functional materials and living neuronal tissues is at the forefront of bio-nanotechnology. Attempts so far have been based on microscope processing of metals, inorganic semiconductors as electrodes or photoactive layers in biased de ...

2011

A hybrid bio-organic interface for neuronal photoactivation

Diego Ghezzi

Interfacing artificial functional materials and living neuronal tissues is at the forefront of bio-nanotechnology. Attempts so far have been based on micro scale processing of metals, inorganic semiconductors as electrodes or photoactive layers in biased d ...

2011

Active tactile exploration using a brain-machine-brain interface

Hannes Bleuler, Solaiman Shokur, Miguel Nicolelis, Mikhail Lebedev

Brain–machine interfaces1, 2 use neuronal activity recorded from the brain to establish direct communication with external actuators, such as prosthetic arms. It is hoped that brain–machine interfaces can be used to restore the normal sensorimotor function ...

2011

Validation of a high-density microelectrode array for acute brain slice recordings

Diego Ghezzi, Luca Berdondini

Microelectrode arrays (MEAs) are employed to study extracellular electrical activity in neuronal tissues. Nevertheless, commercially available MEAs provide a limited number of recording sites and do not allow a precise identification of the spatio-temporal ...

2011

Validation of a high-density microelectrode array for acute brain slice recordings

Diego Ghezzi, Luca Berdondini

2011

Simultaneous neurochemical stimulation and recording using an assembly of biosensor silicon microprobes and SU-8 microinjectors

Nico de Rooij, Peter Van der Wal, Olivier Frey

In this contribution we present multi-channel microinjector arrays fabricated by a reliable three-layer SU-8 process for the local delivery of specific substances into brain tissue. They are designed to be assembled with previously developed. implantable b ...

Elsevier2011

Very High Density Microelectrode Array with Monolithically Integrated Readout Circuits

Alexandre Schmid, Yusuf Leblebici, Neil Joye, Sedigheh Hashemi

This paper presents the hardware realization and modeling of high-density microelectrode arrays including both microelectronic readout amplifiers as well as three-dimensional microelectrodes forming a fully integrated CMOS compatible system enabling resear ...

2010

Flexible and stretchable micro-electrodes for in vitro and in vivo neural interfaces

Stéphanie Lacour

Microelectrode arrays (MEAs) are designed to monitor and/or stimulate extracellularly neuronal activity. However, the biomechanical and structural mismatch between current MEAs and neural tissues remains a challenge for neural interfaces. This article desc ...

2010

Fully differential low-noise amplifier with offset reduction for high-resolution neural signal recording

Pierre-André Farine, Steve Tanner, Urs Alexander Müller

A prototype of a high-density multielectrode array for in vitro recording of electrogenic cell networks has been developed. On a surface of 1.92x1.92mm2, it includes 32x32 pixels with a dimension of 60x60µm2. For local amplification of the sensed extracell ...

2010

Integration of a virtual reality based arm in primary somatosensory cortex

Hannes Bleuler, Solaiman Shokur, Miguel Nicolelis, Mikhail Lebedev

Abstract: Recent advances in brain-machine interfaces (BMIs) have demonstrated the possibility of motor neuroprosthetics directly controlled by brain activity. Ideally neuroprosthetic limbs should be integrated in the body schema of the subject. To explore ...

2010

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