Publications associées à Interaction médicamenteuse

Combinations of beta-Lactam Antibiotics Currently in Clinical Trials Are Efficacious in a DHP-I-Deficient Mouse Model of Tuberculosis Infection

John McKinney, Neeraj Dhar

We report here a dehydropeptidase-deficient murine model of tuberculosis (TB) infection that is able to partially uncover the efficacy of marketed broad-spectrum beta-lactam antibiotics alone and in combination. Reductions of up to 2 log CFU in the lungs o ...

American Society for Microbiology2015

Study of the influence of over-the-counter vitamin supplement intake on urine fluorescence to optimize cancer detection by fluorescence cystoscopy

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Carla Martoccia

Fluorescence cystoscopy (FC) efficiently enhances the detection and improves the therapeutic management of early bladder cancer. During an FC, about 150 ml of water is needed to inflate the bladder. The water is quickly diluted by urine which can be fluore ...

Spie-Soc Photo-Optical Instrumentation Engineers2015

A neural approach to drugs monitoring for personalized medicine

Giovanni De Micheli, Sandro Carrara, Camilla Baj-Rossi, Marius Schirmer

The development of fast and mobile drug detection is an important aspect of personalized medicine. It enables the quick assessment of inter-individual differences in drug metabolism and corresponding adjustments of the dose. Recent developments of amperome ...

2015

Dose-response curve of a microfluidic magnetic bead-based surface coverage sandwich assay

Martinus Gijs, Thomas Lehnert, Matteo Cornaglia, Raphaël Etienne Jean Trouillon, Hüseyin Cumhur Tekin

Magnetic micro-and nanoparticles ('magnetic beads') have been used to advantage in many microfluidic devices for sensitive antigen (Ag) detection. Today, assays that use as read-out of the signal the number count of immobilized beads on a surface for quant ...

Elsevier2015

Bioluminescent sensor proteins for point-of-care therapeutic drug monitoring

Kai Johnsson, Luc Reymond, Luc Patiny, Rudolf Griss, Alberto Schena

For many drugs, finding the balance between efficacy and toxicity requires monitoring their concentrations in the patient's blood. Quantifying drug levels at the bedside or at home would have advantages in terms of therapeutic outcome and convenience, but ...

Nature Publishing Group2014

Deep UV generation and direct DNA photo-interaction by harmonic nanoparticles in labelled samples

Sandrine Gerber, Solène Marcelle Françoise Marie Passemard, Jean-Pierre Wolf, Luigi Bonacina, Daniel Rytz

A biophotonics approach based on the nonlinear optical process of second harmonic generation is presented and demonstrated on malignant human cell lines labelled by harmonic nanoparticles. The method enables independent imaging and therapeutic action, sele ...

Royal Society of Chemistry2014

Low-Dose Vascular Photodynamic Therapy Decreases Tumor Interstitial Fluid Pressure, which Promotes Liposomal Doxorubicin Distribution in a Murine Sarcoma Metastasis Model

Hubert van den Bergh, Georges Wagnières, Laurent Décosterd, Jean Yannis Perentes

Solid tumors are known to have an abnormal vasculature that limits the distribution of chemotherapy. We have recently shown that tumor vessel modulation by low-dose photodynamic therapy (L-PDT) could improve the uptake of macromolecular chemotherapeutic ag ...

Elsevier Science Inc2014

Continuous monitoring of Naproxen by a cytochrome P450-based electrochemical sensor

Giovanni De Micheli, Sandro Carrara, Andrea Cavallini, Camilla Baj-Rossi

This paper reports the characterization of an electrochemical biosensor for the continuous monitoring of Naproxen based on cytochrome P450. The electrochemical biosensor is based on the drop-casting of multi-walled carbon-nanotubes (MWCNTs) and microsomal ...

Elsevier2014

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Interaction médicamenteuse

Combinations of beta-Lactam Antibiotics Currently in Clinical Trials Are Efficacious in a DHP-I-Deficient Mouse Model of Tuberculosis Infection

Nanosensors for early cancer detection and for therapeutic drug monitoring

Study of the influence of over-the-counter vitamin supplement intake on urine fluorescence to optimize cancer detection by fluorescence cystoscopy

A neural approach to drugs monitoring for personalized medicine

Dose-response curve of a microfluidic magnetic bead-based surface coverage sandwich assay

Bioluminescent sensor proteins for point-of-care therapeutic drug monitoring

Oxypurinol directly and immediately activates the drug-specific T cells via the preferential use of HLA-B*58:01

Deep UV generation and direct DNA photo-interaction by harmonic nanoparticles in labelled samples

Low-Dose Vascular Photodynamic Therapy Decreases Tumor Interstitial Fluid Pressure, which Promotes Liposomal Doxorubicin Distribution in a Murine Sarcoma Metastasis Model

Continuous monitoring of Naproxen by a cytochrome P450-based electrochemical sensor

Graph Chatbot

Chattez avec Graph Search

Combinations of beta-Lactam Antibiotics Currently in Clinical Trials Are Efficacious in a DHP-I-Deficient Mouse Model of Tuberculosis Infection

Nanosensors for early cancer detection and for therapeutic drug monitoring

Study of the influence of over-the-counter vitamin supplement intake on urine fluorescence to optimize cancer detection by fluorescence cystoscopy

Dose-response curve of a microfluidic magnetic bead-based surface coverage sandwich assay

A neural approach to drugs monitoring for personalized medicine

Oxypurinol directly and immediately activates the drug-specific T cells via the preferential use of HLA-B*58:01

Bioluminescent sensor proteins for point-of-care therapeutic drug monitoring

Low-Dose Vascular Photodynamic Therapy Decreases Tumor Interstitial Fluid Pressure, which Promotes Liposomal Doxorubicin Distribution in a Murine Sarcoma Metastasis Model

Deep UV generation and direct DNA photo-interaction by harmonic nanoparticles in labelled samples

Continuous monitoring of Naproxen by a cytochrome P450-based electrochemical sensor