Publications associées à Penetrating trauma

A First-in-Human Randomized Study to Assess the Safety, Tolerability, Pharmacokinetics, and Neutralization Profile of Two Investigational Long-Acting Anti-SARS-CoV-2 Monoclonal Antibodies

Introduction: COVID-19 remains a significant risk for the immunocompromised given their lower responsiveness to vaccination or infection. Therefore, passive immunity through long-acting monoclonal antibodies (mAbs) offers a needed approach for pre-exposure ...

2024

Nature of Crack Path Instabilities in Thin Sheets Cut by Blunt Objects

Iryna Sivak

Cutting a brittle thin sheet with a blunt object leaves an oscillating crack that seemingly violates the principle of local symmetry for fracture. We experimentally find that at a critical value of a well chosen control parameter the straight propagation i ...

AMER PHYSICAL SOC2020

Gangliosides: Treatment Avenues in Neurodegenerative Disease

Pierre Magistretti

Gangliosides are cell membrane components, most abundantly in the central nervous system (CNS) where they exert among others neuro-protective and -restorative functions. Clinical development of ganglioside replacement therapy for several neurodegenerative ...

FRONTIERS MEDIA SA2019

Stability enhancement using hyaluronic acid gels for delivery of human fetal progenitor tenocytes

Dominique Pioletti, Alain Farron, Corinne Scaletta, Lee Ann Laurent-Applegate, Anthony Grognuz

Tendon afflictions are very common, and their negative impact is high both at the workplace and in leisure activities. Tendinopathies are increasing in prevalence and can lead to tendon ruptures, where healing is a long process with outcomes that are often ...

2016

Wound repair and regeneration

Yann Barrandon

The repair of wounds is one of the most complex biological processes that occur during human life. After an injury, multiple biological pathways immediately become activated and are synchronized to respond. In human adults, the wound repair process commonl ...

2008

Wound healing gene-family expression differences between fetal and foreskin cells used for bioengineered skin substitutes

Dominique Pioletti, Corinne Scaletta, Lee Ann Laurent-Applegate, Nathalie Hirt-Burri

For tissue engineering, several cell types and tissues have been proposed as starting material. Allogenic skin products available for therapeutic usage are mostly developed with cell culture and with foreskin tissue of young individuals. Fetal skin cells o ...

2008

Wound-healing defect of CD18(-/-) mice due to a decrease in TGF-beta1 and myofibroblast differentiation

Boris Hinz

We studied the mechanisms underlying the severely impaired wound healing associated with human leukocyte-adhesion deficiency syndrome-1 (LAD1) using a murine disease model. In CD18(-/-) mice, healing of full-thickness wounds was severely delayed during gra ...

Nature Publishing Group2005