Publications associées à Subgranular zone

Shedding of neurexin 3 beta ectodomain by ADAM10 releases a soluble fragment that affects the development of newborn neurons

Erika Myrna Borcel Novoa, Patrick Fraering, Mitko Dimitrov, Magda Maria Palczynska, Giorgio Ulrich, Marine Krzisch

Neurexins are transmembrane synaptic cell adhesion molecules involved in the development and maturation of neuronal synapses. In the present study, we report that Nrxn3 beta is processed by the metalloproteases ADAM10, ADAM17, and by the intramembrane-clea ...

Nature Publishing Group2016

Health hazards of methylammonium lead iodide based perovskites: cytotoxicity studies

László Forró, Hilal Lashuel, Endre Horvath, Anne-Laure Mahul Mellier, Massimo Spina, Bohumil Maco, Ryma Iness Benmessaoud

New technologies launch novel materials; besides their performances in products, their health hazards must be tested. This applies to the lead halide perovskite CH3NH3PbI3 as well, which offers fulgurate applications in photovoltaic devices. We report the ...

Royal Soc Chemistry2016

Long Term Hippocampal and Cortical Changes Induced by Maternal Deprivation and Neonatal Leptin Treatment in Male and Female Rats

Erika Myrna Borcel Novoa

Maternal deprivation (MD) during neonatal life has diverse long-term behavioral effects and alters the development of the hippocampus and frontal cortex, with several of these effects being sexually dimorphic. MD animals show a marked reduction in their ci ...

Public Library of Science2015

SOD1 silencing in motoneurons or glia rescues neuromuscular function in ALS mice

Patrick Aebischer, Bernard Schneider, Christopher Towne, Elisabeth Anne Dirren, Cylia Cloé Rochat

Objective: Amyotrophic lateral sclerosis is an incurable disorder mainly characterized by motoneuron degeneration. Mutations in the superoxide dismutase 1 (SOD1) gene account for 20% of familial forms of the disease. Mutant SOD1 exerts multiple pathogenic ...

Wiley-Blackwell2015

Nkx2.1-derived astrocytes and neurons together with Slit2 are indispensable for anterior commissure formation

Elizabeth Anne Allen

Guidepost cells present at and surrounding the midline provide guidance cues that orient the growing axons through commissures. Here we show that the transcription factor Nkx2.1 known to control the specification of GABAergic interneurons also regulates th ...

Nature Publishing Group2015

Mice with ablated adult brain neurogenesis are not impaired in antidepressant response to chronic fluoxetine

Maria del Carmen Sandi Perez

The neurogenesis hypothesis of major depression has two main facets. One states that the illness results from decreased neurogenesis while the other claims that the very functioning of antidepressants depends on increased neurogenesis. In order to verify t ...

Pergamon-Elsevier Science Ltd2014

FOXO3 determines the accumulation of alpha-synuclein and controls the fate of dopaminergic neurons in the substantia nigra

Bernard Schneider, Graham Knott, Juan-Carlos Sarria, Lu Zheng, Emilda Pino, Ryoji Amamoto

Parkinson's disease (PD) is characterized by the selective degeneration of neuronal populations presumably due to pathogenic interactions between aging and predisposing factors such as increased levels of a-synuclein. Here, we genetically modulate the acti ...

Oxford University Press2014

Control of Mitochondrial pH by Uncoupling Protein 4 in Astrocytes Promotes Neuronal Survival

Pierre Magistretti, Hélène Danielle Perreten Lambert, Sylvain Eric Lengacher, Manuel Raphael Zenger, Jean-Yves Chatton

Brain activity is energetically costly and requires a steady and highly regulated flow of energy equivalents between neural cells. It is believed that a substantial share of cerebral glucose, the major source of energy of the brain, will preferentially be ...

American Society for Biochemistry and Molecular Biology2014

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Subgranular zone

Shedding of neurexin 3 beta ectodomain by ADAM10 releases a soluble fragment that affects the development of newborn neurons

Health hazards of methylammonium lead iodide based perovskites: cytotoxicity studies

Long Term Hippocampal and Cortical Changes Induced by Maternal Deprivation and Neonatal Leptin Treatment in Male and Female Rats

SOD1 silencing in motoneurons or glia rescues neuromuscular function in ALS mice

Nkx2.1-derived astrocytes and neurons together with Slit2 are indispensable for anterior commissure formation

Physical exercise rescues adult neurogenesis, synaptic plasticity and memory in down syndrome mice

Mice with ablated adult brain neurogenesis are not impaired in antidepressant response to chronic fluoxetine

Impact of the apolipoprotein E polymorphism, age and sex on neurogenesis in mice: Pathophysiological relevance for Alzheimer's disease?

FOXO3 determines the accumulation of alpha-synuclein and controls the fate of dopaminergic neurons in the substantia nigra

Control of Mitochondrial pH by Uncoupling Protein 4 in Astrocytes Promotes Neuronal Survival

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Chattez avec Graph Search

Long Term Hippocampal and Cortical Changes Induced by Maternal Deprivation and Neonatal Leptin Treatment in Male and Female Rats

Mice with ablated adult brain neurogenesis are not impaired in antidepressant response to chronic fluoxetine

Physical exercise rescues adult neurogenesis, synaptic plasticity and memory in down syndrome mice

Impact of the apolipoprotein E polymorphism, age and sex on neurogenesis in mice: Pathophysiological relevance for Alzheimer's disease?

FOXO3 determines the accumulation of alpha-synuclein and controls the fate of dopaminergic neurons in the substantia nigra

Control of Mitochondrial pH by Uncoupling Protein 4 in Astrocytes Promotes Neuronal Survival

Health hazards of methylammonium lead iodide based perovskites: cytotoxicity studies

SOD1 silencing in motoneurons or glia rescues neuromuscular function in ALS mice

Nkx2.1-derived astrocytes and neurons together with Slit2 are indispensable for anterior commissure formation