Concept
Marge chirurgicale
Personnes associées (12)
Georges Wagnières
Georges Wagnières a obtenu son diplôme (MSc) en physique à l'Université de Lausanne, Suisse, en 1986. Il a reçu son doctorat ès science (PhD) en physique (Optique Biomédicale) de l'Ecole Polytechnique Fédérale de Lausanne (EPFL) en 1992, et a effectué un travail de postdoctorat dans les "Wellman Laboratories of Photomedicine" (Harvard Medical School) situés à Boston, MA, USA, en 1993 et 1994. Il a aussi obtenu, en 2001, un "Master in management of technology" délivré par l'Ecole des Hautes Etudes Commerciales (HEC) de l'Université de Lausanne et l'EPFL. Depuis 1994, il gère un groupe de recherche de l'EPFL actif dans les domaines suivants: - Caractérisation et détection de lésions cancéreuses par spectroscopie et imagerie de fluorescence ainsi que par imagerie à fort grossissement. - Traitement du cancer ainsi que d'autres pathologies associées à des désordres immunologiques (maladie de Crohn, Colite ulcéreuse) ou vasculaires par thérapie photodynamique (PDT). - Développement préclinique et clinique de photosensibilisateurs, de marqueurs fluorescents et d'instruments optiques pour le photodiagnostic. - Traitement de diverses pathologies, y compris les maladies neuro-dégénératives (Parkinson, Alzheimer), par photobiomodulation. - Monitorage de la dose optique pour la PDT basée sur l'imagerie de fluorescence de photosensibilisateurs. - Induction de l'extravasation d'agent chimiothérapeutiques par PDT. - Mesure in vivo de la concentration d'oxygène dans des tissus biologiques par spectroscopie et imagerie optiques résolues en temps. - Monitorage d'un traitement au laser de la rétine par imagerie de reflectance. - Développement de distributeurs de lumière pour des applications biomédicales. - Dosimétrie de lumière / Radiométrie. - Spectroscopie et imagerie en optique biomédicale. Georges Wagnières est aussi co-fondateur et a présidé une société "spin-off" de l'EPFL: - Medlight SA, fondée en 1997, qui développe, produit et commercialise des distributeurs de lumière pour la thérapie photodynamique. Georges Wagnières est l'auteur et co-auteur de plus de 235 articles scientifiques dont 150 ont été publiés dans des revues internationales ayant un comité de relecture (review board). De plus, il est inventeur de 18 brevets. Finalement, il supervise ou a supervisé 12 doctorants et enseigne actuellement à l'EPFL l'optique biomédicale et la photomédecine au niveaux "master". Ces cours sont aussi donnés à l'Ecole doctorale (EDCH, EDSV) de l'EPFL. Finalement, il donne le cours intitulé "Physique Générale I" aux biologistes de première année inscrits à l'Ecole de Biologie de l'Université de Lausanne. PUBLICATIONS PRINCIPALES: SVP visiter: https://www.epfl.ch/labs/lifmet/wagnieres/publications/
Douglas Hanahan
Douglas Hanahan, born in Seattle, Washington, USA, received a bachelors degree in Physics from MIT (1976), and a Ph.D. in Biophysics from Harvard (1983). He worked at Cold Spring Harbor Laboratory in New York (1978-88) initially as a graduate student and then as a group leader. From 1988-2010 he was on the faculty of the Department of Biochemistry & Biophysics at UCSF in San Francisco. He has been elected to the American Academy of Arts & Sciences (2007), the Institute of Medicine (USA) (2008), the US National Academy of Science (2009), and EMBO (2010). In 2011, Hanahan received an honorary degree from the University of Dundee (UK).
Christian Depeursinge
Christian Depeursinge is the leader of the Microvision and Micro-Diagnostics (MVD) group at the Advanced Photonics Laboratory of the Institute of Microengineering at EPFL (Ecole Polytechnique Fédérale de Lausanne), Switzerland (http://apl.epfl.ch/muvision). His research and expertise in biomedical engineering and optics is internationally acknowledged. His current research topics include coherent and incoherent Imaging applied to diagnostics in biology, His research group pioneered in the development of DHM technology. He worked on several projects developed in cooperation with European and international partners. He is author and co-author of over 100 papers published in peer reviewed journals, several book chapters and more than 30 patents. He has given more than 20 invited lectures and plenaries in the last five years. He developed many projects in cooperation with national and international industries. He is co-founder of a start-up company (Lyncée Tec SA: www.Lynceetec.com). He is currently teaching at EPFL and occasionally in foreign universities and institutes.
Claudio Bruschini
Claudio Bruschini holds an MSc in high energy physics from the University of Genova and a PhD in Applied Sciences from the Vrije Universiteit Brussel (VUB). He started his career with INFN (Italy, 1993), in the WA92 CERN collaboration (particle physics), and then moved to CERN as a Fellow in the European GP-MIMD2 project, attached to the NA48 collaboration (particle physics, parallel programming, 1994-1995). He then started his close collaboration with EPFL, first in the DeTeC (Demining Technology Center) project (sensors for landmine detection/humanitarian demining, 1996-1997). After DeTeC's end, he started the first of a series of fruitful collaborations with the Vrije Universiteit Brussel (VUB) on humanitarian demining related R&D (1998). This was followed by the EUDEM survey project (The European Union in Humanitarian Demining, 1998), the EUDEM2 three year EC sponsored support measure (www.eudem.info, 2001-2004), and the DELVE support action (www.delve.vub.ac.be, 2007). In parallel he started working within the EPFL's AQUA group (Advanced Quantum Architectures, Edoardo Charbon), on topics as diverse as ultrasonic sensors for in-air application, optical 3D and high speed 2D sensing, sensor networks, or tracking/motion capture systems, in particular for the preparation of research projects. This culminated in the European MEGAFRAME (www.megaframe.eu, FP6, 2006-2010, SPAD arrays and related in-pixel time stamping electronics in deep submicron CMOS technology) and SPADnet (www.spadnet.eu, FP7, 2010-2014, networked SPAD arrays for Positron Emission Tomography) projects, coordinated by EPFL-AQUA. As from 2009 he also worked with Dario Floreano on the management of the CURVACE Curved Artificial Compound Eyes FP7 project (www.curvace.org), coordinated by EPFL-LIS. He was also active with CHUV (Lausanne University Hospital) within EndoTOFPET-US (endoscopic PET) as well as on a CTI project devoted to the development of a new hand-held standalone tool for tracer-guided medical procedures. In 2014 he had also the pleasure of joining the EPFL ICLAB of Christian Enz during its ramp-up phase, collaborating on device related topics (SNF GigaRadMOST) and biomedical R&D (NanoTera WiseSkin). Claudio is now fully with EPFL’s Advanced Quantum Architecture (AQUA). He has also been active as independent scientific consultant, under the label CBR Scientific Consulting, on the preparation of (European) R&D project proposals and the execution of individual studies, and worked in 2006 for a local start-up as operations manager and R&D advisor.... but this is another story. An unauthorized early biography is available at http://lami.epfl.ch/team/claudiob/...
Edoardo Charbon
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