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The genomic landscape of human cellular circadian variation points to a novel role for the signalosome

Frédéric Bruno Martin Gachon, Konstantin Popadin, Daniel Alain Dominique Marie Mauvoisin

The importance of natural gene expression variation for human behavior is undisputed, but its impact on circadian physiology remains mostly unexplored. Using umbilical cord fibroblasts, we have determined by genome-wide association how common genetic varia ...

Elife Sciences Publications Ltd2017

The Ligand Aspect Ratio as a Decisive Factor for the Self-Assembly of Coordination Cages

Rosario Scopelliti, Kay Severin, Philip Pattison, Euro Solari, Konstantin Zhurov, Suzanne Maria Jansze, Giacomo Cecot, Matthew David Wise, Alba Finelli

It is possible to control the geometry and the composition of metallasupramolecular assemblies via the aspect ratio of their ligands. This point is demonstrated for a series of iron- and palladium-based coordination cages. Functionalized clathrochelate com ...

2016

Determining The Potential Of Salinity Gradient Energy Source Using An Exergy Analysis

Arash Emdadi

Mixing of fresh (river) water and salty water (seawater or saline brine) in a control fashion would produces an electrical energy known as salinity gradient energy (SGE). Two main conversion technologies of SGE are membrane-based processes; pressure retard ...

Amer Soc Mechanical Engineers2016

A heterometallic macrocycle as a redox-controlled molecular hinge

Rosario Scopelliti, Kay Severin, Clément Schouwey, Marcus Papmeyer

The ability to modify the structure of nanoscopic assemblies in a controlled fashion is an important prerequisite for the creation of functional supramolecular systems. Here, we describe a heterometallic Pt2Cu2-macrocycle which behaves as a molecular hinge ...

Royal Society of Chemistry2015

Distributionally Robust Multi-Item Newsvendor Problems with Multimodal Demand Distributions

Daniel Kuhn, Grani Adiwena Hanasusanto

We present a risk-averse multi-dimensional newsvendor model for a class of products whose demands are strongly correlated and subject to fashion trends that are not fully understood at the time when orders are placed. The demand distribution is known to be ...

Springer Verlag2015

Polymer Brushes - Engineered Model Interfaces and Functional Surface Coatings for DNA Biosensing and Electrocatalysis

Tugba Bilgiç Tune

Surface modification by functional coatings has become very attractive to develop and produce platforms with improved chemical and physical properties for various applications. The preparation of functional surface coatings in a well-controlled fashion pla ...

EPFL2015

A New Adjustable Glaucoma Drainage Device

Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin, Stéphane Bigler

PURPOSE. This work is focused on the testing of a new experimental noninvasively adjustable glaucoma drainage device (AGDD) that allows for the control of its outflow resistance to modulate intraocular pressure (IOP) in a customized fashion. METHODS. Six A ...

Association for Research in Vision and Ophthalmology2014

Some considerations on wearable antennas

Anja Skrivervik, Jovanche Trajkovikj

There has been a huge increase in interest for wearable communication devices in the last ten years. Applications are manifold, ranging from rescue to fashion over medical devices and safety, leading to the definition of new standards for Body Area Network ...

Ieee2013

When crowding of crowding leads to uncrowding

Michael Herzog, Bilge Sayim, Mauro Manassi

In object recognition, features are thought to be processed in a hierarchical fashion from low-level analysis (edges and lines) to complex figural processing (shapes and objects). Here, we show that figural processing determines low-level processing. Verni ...

Association for Research in Vision and Ophthalmology2013

On toxic effects of scientific journals

Geoffrey Bodenhausen

The advent of online publishing greatly facilitates the dissemination of scientific results. This revolution might have led to the untimely death of many traditional publishing companies, since today's scientists are perfectly capable of writing, formattin ...

Indian Academy of Science2013

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