Concept

Ectosome

Publications associées (7)

Piezoelectric suspended microchannel resonators

The objective of this PhD thesis is the development of a microfluidic platform for the real-time measurements of the mechanical properties of biological analytes at the single entity level.The systems developed for these purposes consist of piezoelectrical ...

EPFL2022

From Patients to Platelets and Back Again: Pharmacological Approaches to Glycoprotein VI, a Thrilling Antithrombotic Target with Minor Bleeding Risks

Nikolaos Stergiopoulos, Augusto Martins Lima

Despite significant advances in the treatment of thrombogenic diseases, antiplatelet therapies are still associated with a high bleeding risk. Consequently, potential benefits of preventing thromboembolic events by pharmacological agents need to be balance ...

GEORG THIEME VERLAG KG2019

Toward Microfluidic Label-Free Isolation and Enumeration of Circulating Tumor Cells from Blood Samples

Philippe Renaud, Margaux Catherine Marie Duchamp, Camille Alice Raillon, Benoît Xavier Emmanuel Desbiolles

The isolation, analysis, and enumeration of circulating tumor cells (CTCs) from cancer patient blood samples are a paradigm shift for cancer patient diagnosis, prognosis, and treatment monitoring. Most methods used to isolate and enumerate these target cel ...

WILEY2019

Label-free detection of hypoxia-induced extracellular vesicle secretion from MCF-7 cells

Philippe Renaud, Sandro Carrara, Tugba Kilic, Ana Teresa De Sousa Valinhas

Nanoscale extracellular vesicles (EVs) including exosomes (50–150 nm membrane particles) have emerged as promising cancer biomarkers due to the carried genetic information about the parental cells. However the sensitive detection of these vesicles remains ...

2018

Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade

Michele De Palma, Céline Wyser Rmili, Ece Kadioglu, Nicolo Rigamonti, Damya Laoui, Antonino Cassarà

Pathological angiogenesis is a hallmark of cancer and a therapeutic target. Vascular endothelial growth factor A (VEGFA) and angiopoietin-2 (ANGPT2; also known as ANG2) are proangiogenic cytokines that sustain tumor angiogenesis and limit antitumor immunit ...

American Association for the Advancement of Science2017

Microparticles, methods for their preparation and use

Esther Amstad

The invention relates to microparticles comprising a crosslinked gel and methods for making and using same. ...

2013

Development and Characterization of a Microfluidic Chip to Capture Circulating Prostate Cancer Cells

Colette Bichsel

The analysis of circulating tumor cells (CTCs) from the blood of cancer patients promises a better understanding of metastasis formation and tumor phenotypes. CTCs are rare (there is 1 CTC in 1 billion of circulating blood cells) and therefore challenging ...

2011

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