Publications associées à Embryoid body

Harmonic Nanoparticles for Regenerative Research

Jean-Pierre Wolf, Jérôme Extermann, Luigi Bonacina

In this visualized experiment, protocol details are provided for in vitro labeling of human embryonic stem cells (hESC) with second harmonic generation nanoparticles (HNPs). The latter are a new family of probes recently introduced for labeling biological ...

Journal Of Visualized Experiments2014

Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation

Bernard Schneider

Microphthalmia-associated transcription factor (MITF) is a master regulator of pigmented cell survival and differentiation with direct transcriptional links to cell cycle, apoptosis and pigmentation. In mouse, Mitf is expressed early and uniformly in optic ...

Oxford University Press2014

Evolutionally dynamic L1 regulation in embryonic stem cells

Didier Trono, Priscilla Turelli, Julien Léonard Duc, Marc Samuel Friedli, Adamantia Kapopoulou, Gabriela Ecco, Andrea Coluccio, Suk Min Jang

Mobile elements are important evolutionary forces that challenge genomic integrity. Long interspersed element-1 (L1, also known as LINE-1) is the only autonomous transposon still active in the human genome. It displays an unusual pattern of evolution, with ...

Cold Spring Harbor Lab Press, Publications Dept2014

Nodal.Gdf1 Heterodimers with Bound Prodomains Enable Serum-independent Nodal Signaling and Endoderm Differentiation

Daniel Constam, Christophe Fuerer

The TGF beta family member Nodal is central to control pluripotent stem cell fate, but its use as a stem cell differentiation factor is limited by low specific activity. During development, Nodal depends on growth and differentiation factor (Gdf)-1 and on ...

American Society for Biochemistry and Molecular Biology2014

A doppler effect in embryonic pattern formation

Andrew Charles Oates, Daniele Soroldoni

During embryonic development, temporal and spatial cues are coordinated to generate a segmented body axis. In sequentially segmenting animals, the rhythm of segmentation is reported to be controlled by the time scale of genetic oscillations that periodical ...

2014

Development of bioactive hydrogel capsules for the 3D expansion of pluripotent stem cells in bioreactors

Matthias Lütolf, Yoji Tabata

Pluripotent stem cells hold great promise for many pharmaceutical and therapeutic applications. However, the lack of scalable methodologies to expand these cells to clinically relevant numbers is a major roadblock in realizing their full potential. To addr ...

Royal Soc Chemistry2014

Embryonic stem cell-based screen for small molecules: cluster analysis reveals four response patterns in developing neural cells

David Michael Suter, Mathurin Baquié

Neural differentiation of embryonic stem cells (ESC) is considered a promising model to perform in vitro testing for neuroactive and neurotoxic compounds. We studied the potential of a dual reporter murine ESC line to identify bioactive and/or toxic compou ...

2013

Patterning of cell-instructive hydrogels by hydrodynamic flow focusing

Matthias Lütolf, Steffen Cosson, Simone Allazetta

Microfluidic gradient systems offer a very precise means to probe the response of cells to graded biomolecular signals in vitro, for example to model how morphogen proteins affect cell fate during developmental processes. However, existing gradient makers ...

Royal Society of Chemistry2013

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Embryoid body

Dynamic Reorganization of Extremely Long-Range Promoter-Promoter Interactions between Two States of Pluripotency

Harmonic Nanoparticles for Regenerative Research

Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation

Evolutionally dynamic L1 regulation in embryonic stem cells

Nodal.Gdf1 Heterodimers with Bound Prodomains Enable Serum-independent Nodal Signaling and Endoderm Differentiation

A doppler effect in embryonic pattern formation

Development of bioactive hydrogel capsules for the 3D expansion of pluripotent stem cells in bioreactors

Embryonic stem cell-based screen for small molecules: cluster analysis reveals four response patterns in developing neural cells

Pyramidal Neurons Derived from Human Pluripotent Stem Cells Integrate Efficiently into Mouse Brain Circuits In Vivo

Patterning of cell-instructive hydrogels by hydrodynamic flow focusing

Graph Chatbot

Chattez avec Graph Search

Dynamic Reorganization of Extremely Long-Range Promoter-Promoter Interactions between Two States of Pluripotency

Nodal.Gdf1 Heterodimers with Bound Prodomains Enable Serum-independent Nodal Signaling and Endoderm Differentiation

A doppler effect in embryonic pattern formation

Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation

Patterning of cell-instructive hydrogels by hydrodynamic flow focusing

Harmonic Nanoparticles for Regenerative Research

Evolutionally dynamic L1 regulation in embryonic stem cells

Embryonic stem cell-based screen for small molecules: cluster analysis reveals four response patterns in developing neural cells

Development of bioactive hydrogel capsules for the 3D expansion of pluripotent stem cells in bioreactors

Pyramidal Neurons Derived from Human Pluripotent Stem Cells Integrate Efficiently into Mouse Brain Circuits In Vivo