Publications associées à Loose connective tissue

Proliferation-driven mechanical compression induces signalling centre formation during mammalian organ development

Localized sources of morphogens, called signalling centres, play a fundamental role in coordinating tissue growth and cell fate specification during organogenesis. However, how these signalling centres are established in tissues during embryonic developmen ...

Nature Portfolio2024

Hippo-YAP/TAZ signalling coordinates adipose plasticity and energy balance by uncoupling leptin expression from fat mass

Johan Auwerx, Xiaoxu Li, Maroun Bou Sleiman, Jun Yong Kim, Yoo Hoon Kim

Adipose tissues serve as an energy reservoir and endocrine organ, yet the mechanisms that coordinate these functions remain elusive. Here, we show that the transcriptional coregulators, YAP and TAZ, uncouple fat mass from leptin levels and regulate adipocy ...

Nature Portfolio2024

Mimicking Loading-Induced Cartilage Self-Heating in Vitro Promotes Matrix Formation in Chondrocyte-Laden Constructs with Different Mechanical Properties

Dominique Pioletti, Peyman Karami, Naser Nasrollahzadeh Mamaghani, Theofanis Stampoultzis, Yanheng Guo

Articular cartilage presents a mechanically sensitive tissue. Chondrocytes, the sole cell type residing in the tissue, perceive and react to physical cues as signals that significantly modulate their behavior. Hyaline cartilage is a connective tissue with ...

2023

Biodegradable Implantable Microsystems

Jürgen Brugger, Jongeon Park

Biodegradable implanted devices and microsystems are candidates to fulfill the utmost required in-vivo assistance for a variety of envisioned bio-medical health care applications. They range from monitoring biomarkers, recording, and stimulation, to local ...

IEEE2023

Development of next-generation microfluidic systems for enhanced, faster, and cost-effective immunoassays for tissue diagnostics - Ac electrothermal flow & Acoustofluidics

Muaz Salama Abdelmonem Draz

The application of microfluidics in the field of surface-based assays and more specifically, the spatial molecular profiling of tumor tissues has gained a lot of interest, especially with the increased interest in personalized medicine and targeted therapy ...

EPFL2023

Brain Fingerprinting Using Fmri Spectral Signatures On High-Resolution Cortical Graphs

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti, Hamid Behjat, Stefano Moia, Carlo Ferritto

Resting-state fMRI has proven to entail subject-specific signatures that can serve as a fingerprint to identify individuals. Conventional methods are based on building a connectivity matrix based on correlation between the average time course of pairs of b ...

IEEE2023

Aging Fly Cell Atlas identifies exhaustive aging features at cellular resolution

Maria Brbic, Sandy Lee

Aging is characterized by a decline in tissue function, but the underlying changes at cellular resolution across the organism remain unclear. Here, we present the Aging Fly Cell Atlas, a single-nucleus transcriptomic map of the whole aging Drosophila. We c ...

American Association for the Advancement of Science2023

Cortical cell assemblies and their underlying connectivity: an in silico study

Michael Reimann, András Ecker, Sirio Bolaños Puchet, James Bryden Isbister, Daniela Egas Santander

Recent developments in experimental techniques have enabled simultaneous recordings from thousands of neurons, enabling the study of functional cell assemblies. However, determining the patterns of synaptic connectivity giving rise to these assemblies rema ...

2024

Method for labelling a device and devices obtanaible therefrom

Nicolas Vachicouras, Florian Dylan Fallegger, Ludovic Serex

Disclosed herein is a method for labelling a portion of a device, said method comprising the steps of providing a first substrate layer of a transparent or translucent material, depositing a first coloured material onto said first substrate layer in a labe ...

2022

Inferring the flow properties of epithelial tissues from their geometry

Matthieu Wyart, Marko Popovic, Valentin Camille Druelle

Amorphous materials exhibit complex material properties with strongly nonlinear behaviors. Below a yield stress they behave as plastic solids, while they start to yield above a critical stress sigma(c). A key quantity controlling plasticity which is, howev ...

2021