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Publications associées (7)
Smart Portable Pen for Continuous Monitoring of Anaesthetics in Human Serum With Machine Learning
Sandro Carrara, Mandresy Ivan Ny Hanitra, Danilo Demarchi, Simone Aiassa
Continuous monitoring of anaesthetics infusion is demanded by anaesthesiologists to help in defining personalized dose, hence reducing risks and side effects. We propose the first piece of technology tailored explicitly to close the loop between anaesthesi ...
2021Quasi-Digital Biosensor-Interface for a Portable Pen to Monitor Anaesthetics Delivery
Sandro Carrara, Francesca Stradolini, Danilo Demarchi, Abuduwaili Tuoheti, Simone Aiassa
Monitoring of patient response to the anaesthetic drugs is an attractive improvement for achieving a correct balance of sedation level, increasing the chance of success in the right procedure of anaesthesia. Nowadays, there are no commercial tools able to ...
IEEE2019Live Demonstration: Quasi-Digital Portable Pen to Monitor Anaesthetics Delivery
Sandro Carrara, Danilo Demarchi, Simone Aiassa, Francesco Grassi
The live demonstration presents the innovative concept of a portable pen-device able to sense anaesthetic compounds over time for improved anaesthesiology practice. A custom Printed Circuit Board (PCB) manage in the event-based quasi-digital domain the sam ...
IEEE2019IoT Bio-Electronic Multi-Panel Device for On-line Monitoring of Anaesthesia Delivery
After a failure of "One-Size-Fits-All" approach on traditional treatment of diseases, the age of multi-faceted personalized medicine came into being for tailoring therapy to get the best response in the highest safety margin. Personalized drug dosage is on ...
EPFL2018Cascaded PID controller for anaesthesia delivery
The technologies for continuous measurement of the anaesthetic agents circulating in body fluids are not mature yet, though some preliminary prototypes exist already. We present a control algorithm that based on the real measurement of propofol plasma conc ...
2016Targeting Tumor Vasculature with Aptamer-Functionalized Doxorubicin - Polylactide Nanoconjugates for Enhanced Cancer Therapy
An A10 aptamer (Apt)-functionalized, sub-100 nm doxorubicin–polylactide (Doxo-PLA) nanoconjugate (NC) with controlled release profile was developed as an intravenous therapeutic strategy to effectively target and cytoreduce canine hemangiosarcoma (cHSA), a ...
American Chemical Society2015Modeling the effects of midazolam on cortical and thalamic neurons
Controversy exists regarding the site where anesthetics act in the brain to produce sedation and unconsciousness. Actions in the cerebral cortex and thalamus are likely, although the relative importance of each site is unclear. We used in computo modeling ...
2009