Publications associées (236)

Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo

Gab1 is a multiadaptor protein that has been shown to be required for multiple processes in embryonic development and oncogenic transformation. Gab1 functions by amplifying signal transduction downstream of various receptor tyrosine kinases through recruit ...
2007

Interactions between HOXD and Gli3 genes control the limb apical ectodermal ridge via Fgf10

Denis Duboule, Jozsef Zakany

The development of the vertebrate limb is dependent upon two signaling centers, the apical ectodermal ridge (AER), which provides the underlying mesenchyme with essential growth factors, and the zone of polarizing activity (ZPA), the source of the Sonic he ...
2007

Masters and servants of the force: the role of matrix adhesions in myofibroblast force perception and transmission

Boris Hinz

Fibroblast-to-myofibroblast differentiation - a key event in the development of fibrocontractive diseases and in wound granulation tissue contraction - is hallmarked by the formation of stress fibers and the neo-expression of alpha-smooth muscle actin. Inc ...
Elsevier2006

Metabolic engineering under uncertainty-II: Analysis of yeast metabolism

Vassily Hatzimanikatis

Yeast metab. has been used extensively in scientific investigations and industrial applications. Understanding the properties of the yeast metabolic network is crucial, yet unaccomplished due to its high complexity, the different culture conditions, and th ...
2006

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