Concept

Acide hyaluronique

Publications associées (66)

Engineered aprotinin for improved stability of fibrin biomaterials

Peter Frey, Stephane Kontos, Jeffrey Alan Hubbell, Kristen Lorentz

Fibrin has been long used clinically for hemostasis and sealing, yet extension of use in other applications has been limited due to its relatively rapid resorption in vivo, even with addition of aprotinin or other protease inhibitors. We report an engineer ...

2011

Macrophage regulation of tumor angiogenesis: implications for cancer therapy

Michele De Palma, Mario Leonardo Squadrito

This article reviews the evidence for macrophages playing an important role in the regulation of tumor angiogenesis. Findings in mouse models show that macrophages promote angiogenesis in tumors both by producing excessive amounts of proangiogenic factors ...

2011

Skeletal growth, ultrastructure and composition of the azooxanthellate scleractinian coral Balanophyllia regia

Anders Meibom, Jaroslaw Hubert Stolarski, Isabelle Domart-Coulon

The biomineralization process and skeletal growth dynamics of azooxanthellate corals are poorly known. Here, the growth rate of the shallow-water dendrophyllid scleractinian coral Balanophyllia regia was evaluated with calcein-labeling experiments that sho ...

2010

Biomechanical regulation of blood vessel growth during tissue vascularization

Witold Waldemar Kilarski

Formation of new vessels in granulation tissue during wound healing has been assumed to occur solely through sprouting angiogenesis. In contrast, we show here that neovascularization can be accomplished by nonangiogenic expansion of preexisting vessels. Us ...

2009

Gene delivery from responsive hyaluronic acid hydrogels for directed angiogenesis

Arnaud Felber

Tissue Engineering points to maintain, restore or to improve and create new tissues. This purpose typically involves the selection of a natural or synthetic biomaterial as a scaffold to create the biological substitutes. Furthermore, angiogenesis, the grow ...

2008

Synthetic biomaterials as cell-responsive artificial extracellular matrices

Matthias Lütolf, Jeffrey Alan Hubbell

Cells in our tissues are exposed to complex arrays of biochemical and biophysical cues from their protein- and sugar-rich extracellular matrix (ECM). In concert with cell- intrinsic regulatory cascades, these temporally and spatially coordinated signals in ...

Imperial College Press2008

The myofibroblast: one function, multiple origins

Boris Hinz

The crucial role played by the myofibroblast in wound healing and pathological organ remodeling is well established; the general mechanisms of extracellular matrix synthesis and of tension production by this cell have been amply clarified. This review disc ...

American Society for Investigative Pathology2007

Biomechanical evaluation of intra-articular and extra-articular procedures in anterior cruciate ligament reconstruction: A finite element analysis

Dominique Pioletti, Perrine Saunier

Background. Intra-articular techniques (single and double bundles) are the most widely used procedures for the anterior cruciate lig- ament reconstruction. Lemaire introduced in 1967 the extra-articular techniques, and combined intra-articular and extra-ar ...

2007

Multilayer-Assembled Microchip for Enzyme Immobilization as Reactor Toward Low-Level Protein Identification

Hubert Girault

A microchip reactor has been developed on the basis of a layer-by-layer approach for fast and sensitive digestion of proteins. The resulting peptide analysis has been carried out by matrix-assisted laser desorption ionization timeof- flight mass spectromet ...

2006

Contraction of myofibroblasts in granulation tissue is dependent on Rho/Rho kinase/myosin light chain phosphatase activity

Boris Hinz, Michael David Martin

During wound healing and fibrocontractive diseases fibroblasts acquire a smooth muscle cell-like phenotype by differentiating into contractile force generating myofibroblasts. We examined whether regulation of myofibroblast contraction in granulation tissu ...

Wiley-Blackwell2006

Graph Chatbot

Chattez avec Graph Search

Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.

AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.

Connectez-vous pour utiliser Chat avec Graph Search