Publications associées à Organisation panaméricaine de la santé

Convalescent human plasma candidate reference materials protect against Crimean-Congo haemorrhagic fever virus (CCHFV) challenge in an A129 mouse model

Crimean-Congo Haemorrhagic Fever Virus (CCHFV) is spread by infected ticks or direct contact with blood, tissues and fluids from infected patients or livestock. Infection with CCHFV causes severe haemorrhagic fever in humans which is fatal in up to 83 % of ...

Elsevier2024

Inactivation of influenza A virus in expiratory droplets and aerosol particles and the associated physicochemical drivers

Aline Laetitia Schaub

Influenza is an infectious respiratory illness caused by influenza viruses. Every year, it causes up to one billion cases of disease worldwide. Despite its high disease burden, the transmission pathway of influenza remains subject to debate. There is incre ...

EPFL2024

Clusters of science and health related Twitter users become more isolated during the COVID-19 pandemic

Marcel Salathé, Martin Mathias Müller, Martin Müller

COVID-19 represents the most severe global crisis to date whose public conversation can be studied in real time. To do so, we use a data set of over 350 million tweets and retweets posted by over 26 million English speaking Twitter users from January 13 to ...

Nature Portfolio2021

Automatic detection of potential mosquito breeding sites from aerial images acquired by unmanned aerial vehicles

Vitor Pessoa Colombo

The World Health Organization (WHO) has stated that effective vector control measures are critical to achieving and sustaining reduction of vector-borne infectious disease incidence. Unmanned aerial vehicles (UAVs), popularly known as drones, can be an imp ...

2021

Virucidal nanomaterials against influenza

Özgün Kocabiyik

Influenza affects millions of people in all parts of the world. The fact that influenza virus can spread through air increases the chance of influenza outbreaks. There are 3 to 5 million severe cases of influenza resulting in 290,000 to 650,000 deaths ever ...

EPFL2019

Preventive chemotherapy to control soil-transmitted helminthiasis averted more than 500 000 DALYs in 2015

Background: Preventive chemotherapy (PC), the large-scale administration of anthelminthics, is recommended by the World Health Organization (WHO) for the control of soil-transmitted helminthiasis (STH). Since 2010, donated anthelminthics for STH have boost ...

Oxford University Press2018

The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis

Giulia Manina

The re-emergence of tuberculosis in recent years led the World Health Organization (WHO) to launch the Stop TB Strategy program. Beside repurposing the existing drugs and exploring novel molecular combinations, an essential step to face the burden of tuber ...

Springer2013

The World Health Organization Headquarters in Geneva (1960-1966): how mechanical and electrical services are integral to reading built form

Giulia Marino

The permanent headquarters of the World Health Organizatio, in Geneva, is recognised as one of the major works of Jean Tschumi, who won the international competition in 1960. Shaped by the imposing linear block housing the Secretariat and the Conference Ha ...

Picard2012

Leads for antitubercular compounds from kinase inhibitor library screens

Stewart Cole, Gerardo Turcatti, Marc Chambon, Damiano Banfi, Ruben Hartkoorn, Sophie Magnet, Edina Rita Székely

Discovering new drugs to treat tuberculosis more efficiently and to overcome multidrug resistance is a world health priority. To find antimycobacterial scaffolds, we screened a kinase inhibitor library of more than 12,000 compounds using an integrated stra ...

2010

Towards anti-virulence drugs targeting ESX-1 mediated pathogenesis of Mycobacterium tuberculosis

Stewart Cole, Florence Pojer, Benjamin Blasco, Jeffrey Chen

Mycobacterium tuberculosis (M. tb) the causative agent of tuberculosis (TB) causes 1.7 million deaths annually. According to the World Health Organization, in some areas of the world, 25% of TB cases are due to multi- or extensively drug resistant M. tb st ...

Elsevier2010