Publications associées à Écologie évolutive

Impact of population size on early adaptation in rugged fitness landscapes

Anne-Florence Raphaëlle Bitbol, Richard Marie Servajean

Owing to stochastic fluctuations arising from finite population size, known as genetic drift, the ability of a population to explore a rugged fitness landscape depends on its size. In the weak mutation regime, while the mean steady-state fitness increases ...

ROYAL SOC2023

Active Site-Induced Evolutionary Constraints Follow Fold Polarity Principles in Soluble Globular Enzymes

Matteo Dal Peraro, Luciano Andres Abriata, Alexander Mayorov

A recent analysis of evolutionary rates in >500 globular soluble enzymes revealed pervasive conservation gradients toward catalytic residues. By looking at amino acid preference profiles rather than evolutionary rates in the same data set, we quantified th ...

OXFORD UNIV PRESS2019

Eco-Evolutionary Dynamics Linked to Horizontal Gene Transfer in Vibrios

Melanie Blokesch, Frédérique Marie Jeanne Le Roux

Vibrio is a genus of ubiquitous heterotrophic bacteria found in aquatic environments. Although they are a small percentage of the bacteria in these environments, vibrios can predominate during blooms. Vibrios also play important roles in the degradation of ...

2018

A heterogeneous evolutionary stable population under assortative matching: Exploring the diversity of preferences

Boris Thurm, Charles Chadi Ayoubi

Recent studies have shown that a population acting not only upon self-interest but also exhibiting some morality preference has an evolutionary advantage. Specifically, in the setting of a symmetric fitness game, a resident population is evolutionary stabl ...

2017

Antiviral drug resistance as an adaptive process

Kristen Kay Irwin, Jeffrey David Jensen

Antiviral drug resistance is a matter of great clinical importance that, historically, has been investigated mostly from a virological perspective. Although the proximate mechanisms of resistance can be readily uncovered using these methods, larger evoluti ...

Oxford University Press2016

Inferring the Evolutionary History of Primate microRNA Binding Sites: Overcoming Motif Counting Biases

Jeffrey David Jensen, Feng Gao

The first microRNAs (miRNAs) were identified as essential, conserved regulators of gene expression, targeting the same genes across nearly all bilaterians. However, there are also prominent examples of conserved miRNAs whose functions appear to have shifte ...

Oxford Univ Press2014

Theoretical and Experimental Studies of Dendritic Metacommunities

Francesco Carrara

The present thesis deals with the understanding of the origins and the mechanisms of maintenance of biodiversity in natural landscapes, in particular by identifying key processes that define large-scale patterns of abundance and diversity. Biological commu ...

EPFL2013

ProPhyC: a probabilistic phylogenetic model for refining regulatory networks

Bernard Moret, Xiuwei Zhang

The experimental determination of transcriptional regulatory networks in the laboratory remains difficult and time-consuming, while computational methods to infer these networks provide only modest accuracy. The latter can be attributed in part to the limi ...

Springer Verlag2011

Refining transcriptional regulatory networks using network evolutionary models and gene histories

Bernard Moret, Xiuwei Zhang

Background: Computational inference of transcriptional regulatory networks remains a challenging problem, in part due to the lack of strong network models. In this paper we present evolutionary approaches to improve the inference of regulatory networks for ...

2010

Multi-cellular reconfigurable circuits : evolution, morphogenesis and learning

Daniel Roggen

Bio-inspired electronic circuits have the potential to address some of the shortcomings of conventional electronic circuits, such as lack of applicability to ill-defined problems, of robustness, or of adaptivity to unexpectedly changing environments. Bio-i ...

EPFL2005