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Publications associées (83)
Back-to-Africa introductions of Mycobacterium tuberculosis as the main cause of tuberculosis in Dar es Salaam, Tanzania
In settings with high tuberculosis (TB) endemicity, distinct genotypes of the Mycobacterium tuberculosis complex (MTBC) often differ in prevalence. However, the factors leading to these differences remain poorly understood. Here we studied the MTBC populat ...
PUBLIC LIBRARY SCIENCE2023Selective elimination of enterovirus genotypes by activated sludge and chlorination
Enteroviruses, which are commonly circulating viruses shed in the stool, are released into the sewage system and only partially removed or inactivated, resulting in the discharge of infectious enteroviruses into the environment. Activated sludge and chlori ...
2023A tool for mapping microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes
Kathryn Hess Bellwald, Lida Kanari, Martina Scolamiero
Environmental cues influence the highly dynamic morphology of microglia. Strategies to characterize these changes usually involve user-selected morphometric features, which preclude the identification of a spectrum of context-dependent morphological phenot ...
NATURE PORTFOLIO2022Using population-specific add-on polymorphisms to improve genotype imputation in underrepresented populations
Jacques Fellay, Zhi Ming Xu, Sina Rüeger
Genome-wide association studies rely on the statistical inference of untyped variants, called imputation, to increase the coverage of genotyping arrays. However, the results are often suboptimal in populations underrepresented in existing reference panels ...
San Francisco2022