Concept
Mouton de Soay
Publications associées (10)
Rapid identification and interpretation of gene‐environment associations using the new R.SamBada landscape genomics pipeline
Stéphane Joost, Oliver Michele Selmoni, Estelle Rochat, Sylvie Stucki, Kevin Leempoel, Elia Vajana
Samβada is a genome‐environment association (GEA) software, designed to search for signatures of local adaptation. However, pre‐ and post‐processing of data can be labour‐intensive, preventing wider uptake of the method. We have now developed R.SamBada, an ...
2019Optimizing Carbon Storage Within a Spatially Heterogeneous Upland Grassland Through Sheep Grazing Management
Livestock grazing is known to influence carbon (C) storage in vegetation and soil. Yet, for grazing management to be used to optimize C storage, large scale investigations that take into account the typically heterogeneous distribution of grazers and C acr ...
Springer2014Adaptations to Climate-Mediated Selective Pressures in Sheep
Following domestication, sheep (Ovis aries) have become essential farmed animals across the world through adaptation to a diverse range of environments and varied production systems. Climate-mediated selective pressure has shaped phenotypic variation and h ...
Oxford Univ Press2014Genome-wide patterns of adaptation to climate-mediated selective pressures in sheep
Sheep (Ovis aries) have been well adapted to thrive in a diverse range of climates during the domestication and breed development process. These climate-mediated selective pressures have shown to influence phenotypic variation within and among breeds and, ...
2014Prenatally engineered autologous amniotic fluid stem cell-based heart valves in the fetal circulation
Peter Modregger, Marco Stampanoni, Markus Rudin, Chad Brokopp, Marc Farine
Prenatal heart valve interventions aiming at the early and systematic correction of congenital cardiac malformations represent a promising treatment option in maternal-fetal care. However, definite fetal valve replacements require growing implants adaptive ...
2012Genetic Diversity of Sheep Breeds from Albania, Greece, and Italy Assessed by Mitochondrial DNA and Nuclear Polymorphisms (SNPs)
We employed mtDNA and nuclear SNPs to investigate the genetic diversity of sheep breeds of three countries of the Mediterranean basin: Albania, Greece, and Italy. In total, 154 unique mtDNA haplotypes were detected by means of D-loop sequence analysis. The ...
2011Assessment of a sheep animal model to optimize photodynamic therapy with Foscan in the esophague
Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, François André Borle
Precursor lesions of oesophagus adenocarcinoma constitute a clinical dilemma. Photodynamic therapy (PDT) is an effective treatment for this indication, but it is difficult to optimise without an appropriate animal model. For this reason, we assessed the sh ...
Wiley-Blackwell2009Atrial Repolarization Alternans in a Chronic Sheep Model of Pacing-Induced Atrial Fibrillation
Jean-Marc Vesin, Florian Jousset, Etienne Pruvot
In pacing-induced models of atrial fibrillation (AF) that mimic atrial high-frequency foci, the increase in AF susceptibility over time is not paralleled by any increase in dispersion of repolarization (DOR). Measurements of effective refractory periods (E ...
2009Detecting footprints of selection in Ovis aries by a spatial analysis approach
Detecting adaptive loci in the genome is essential as it gives the possibility to understand what proportion of a genome or which genes are under the pressure of natural selection. In this paper, we used a Spatial Analysis Method (SAM) recently developed t ...
Edizioni Avenue Media2007Engineering of human meniscus substitute
Injuries to the meniscus are often treated by partial or total meniscectomy, which is known to be associated with detrimental changes in joint function, ultimately increasing the risk of early degenerative joint diseases. Surgical approaches currently in u ...
EPFL2006