Graham KnottGraham Knott received his degree in physiology from the University of Southampton, UK, in 1990, and his PhD in neuroscience from the University of Tasmania, Australia, in 1995. He moved to the University of Lausanne in Switzerland in 1999 where he researched the plasticity of neuronal connectivity in the adult brain, developing correlative light and electron microscopy methods for the analysis of in vivo imaged neurons. In 2006 Graham joined the Ecole Polytechnique Fédérale de Lausanne, establishing the Bio Electron Microscopy Facility and has continued his research interests in brain plasticity and 3D electron microscopy.
Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Andreas MortensenAndreas Mortensen is currently Professor and Director of the Institute of Materials at the Swiss Federal Institute of Technology in Lausanne (EPFL), where he heads the Laboratory for Mechanical Metallurgy. He joined the faculty of EPFL 1997 after ten years, from 1986 to 1996, as a member of the faculty of the Department of Materials Science and Engineering at the Massachusetts Institute of Technology, where he held the successive titles of ALCOA Assistant Professor, Associate Professor, and Professor. His research is focussed on the processing, microstructural development and mechanical behavior of advanced metallic materials with particular focus on metal matrix composites and metal foams, on infiltration processing and capillarity, and on damage and fracture in metallic materials. He is author or co-author of two monographs, around one hundred and eighty scientific or technical publications and twelve patents. Born in San Francisco in 1957, of dual (Danish and US) nationality, Andreas Mortensen graduated in 1980 from the Ecole Nationale Supérieure des Mines de Paris with a Diplôme dIngénieur Civil, and earned his Ph.D. in the Department of Materials Science and Engineering at MIT in 1986. Besides his academic employment, he was a postdoctoral researcher at Nippon Steel during part of 1986, and was invited professor at the Ecole des Mines in Paris during the academic year 1995 to 1996. He is a member of the editorial committee of International Materials Reviews and has co-edited four books. He is a Fellow of ASM, a recipient of the Howe Medal and the Grossman Award of the American Society of Metals, was awarded the Péchiney Prize by the French Academy of Sciences and the Res Metallica Chair from the Katholieke Universiteit Leuven, received three EPFL teaching awards, is one of ISIs Highly Cited authors for Materials Science since 2002 and was awarded an ERC advanced grant in 2012.
Anders MeibomAnders Meibom obtained his PhD in physics from the University of Southern Denmark in 1997. This was followed by two and a half years of PostDoc work at the Hawaii Institute for Geophysics and Planetology, where he conducted mineralogical studies of primitive chondritic meteorites. From 2000 to 2005, he was Research Associate in the Geological & Environmental Sciences, Stanford University, where he represented Stanford in the USGS-Stanford ion microprobe laboratory. In 2005, he became proifessor at the Muséum National dHistoire Naturelle in Paris. From 2006 to 2011 he was the director of the French national NanoSIMS laboratory. Since January 2012, he is professor at the EPFL in the School of Architecture, Civil and Environmental Engineering (ENAC). From April 2014, he is professor ad personam at the Institute of Earth Sciences, University of Lausanne.
Cathrin BriskenCathrin Brisken, MD, PhD, is Associate Professor of Life Sciences at the Swiss Federal Institute of Technology Lausanne (EPFL). Dr. Brisken is internationally recognized for her work on endocrine control of mammary gland development and breast carcinogenesis.
Dr. Brisken received her MD and her PhD degree in Biophysics from the Georg August University of Göttingen, Germany. She completed her postdoctoral work in cancer biology with Dr. R.A. Weinberg at the Whitehead Institute of Biomedical Research in Cambridge, MA, USA. She previously held appointments at the Cancer Center of the Massachusetts General Hospital, Harvard Medical School, Boston and the Swiss Institute for Experimental Cancer Research (ISREC).
Research in Dr. Brisken’s laboratory focuses on the cellular and molecular underpinnings of estrogen and progesterone receptor signaling in the breast and the respective roles of these hormones and hormonally active compounds in carcinogenesis. The aim is to understand how recurrent exposures to endogenous and exogenous hormones contribute to breast carcinogenesis in order to better prevent and treat the disease. The laboratory has pioneered in vivo approaches to genetically dissect the role of the reproductive hormones in driving mouse mammary gland development and shown how they control intercellular communication. Dr. Brisken’s group has developed ex vivo and humanized mouse models using patient samples to study hormone action in human tissues in normal settings and during disease progression.
Dr. Brisken is member of the International Breast Cancer Study Group (IBCSG) Biological Protocol Working Group. She served as Dean of EPFL Doctoral School (more than 2000 PhD students in 18 PhD programs), as member of the Hinterzartener Kreis, the oncology think-tank associated with the German Science Foundation, and numerous Swiss, European, and AACR committees. She co-founded the International Cancer Prevention Institute.
