Publications associées à Foyer ectopique

Active force generation contributes to the complexity of spontaneous activity and to the response to stretch of murine cardiomyocyte cultures

Cardiomyocyte cultures exhibit spontaneous electrical and contractile activity, as in a natural cardiac pacemaker. In such preparations, beat rate variability exhibits features similar to those of heart rate variability in vivo. Mechanical deformations and ...

WILEY2022

A Computational Study of the Electrophysiological Substrate in Patients Suffering From Atrial Fibrillation

Alfio Quarteroni, Andrea Manzoni

In the context of cardiac electrophysiology, we propose a novel computational approach to highlight and explain the long-debated mechanisms behind atrial fibrillation (AF) and to reliably numerically predict its induction and sustainment. A key role is pla ...

FRONTIERS MEDIA SA2021

Nanovolcano microelectrode arrays: toward long-term on-demand registration of transmembrane action potentials by controlled electroporation

Philippe Renaud, Arnaud Bertsch, Benoît Xavier Emmanuel Desbiolles, Nicolas Grégoire Maïno, Stephan Rohr, Etienne de Coulon

Volcano-shaped microelectrodes (nanovolcanoes) functionalized with nanopatterned self-assembled monolayers have recently been demonstrated to report cardiomyocyte action potentials after gaining spontaneous intracellular access. These nanovolcanoes exhibit ...

2020

Development of Implantable Electrodes Based on Polymer Derived Ceramics

Jonas Grossenbacher

The invention of heart pacemakers in the 50's aims to help patients to overcome heart strokes, which represent the first cause of death worldwide. In Europe and in the USA, more than 3000 pacemakers are implanted every day. Despite the constant evolution o ...

EPFL2015

Right insular damage decreases heartbeat awareness and alters cardio-visual effects on bodily self-consciousness

Olaf Blanke, Bruno Herbelin, Roberta Ronchi, Javier Bello Ruiz, Marta Lukowska

Recent evidence suggests that multisensory integration of bodily signals involving exteroceptive or interoceptive information modulates bodily aspects of self-consciousness such as self-identification and self-location. In the so-called full body illusion ...

Pergamon-Elsevier Science Ltd2015

Activity Level of an Atrial Ectopic Focus Observed Through the Equivalent Dipole: a Biophysical Model

Jean-Marc Vesin, Vincent Jacquemet, Mathieu Lemay, Cédric Duchene

Quantifying the role of atrial ectopic foci in the initiation and the maintenance of atrial fibrillation (AF) is a relevant clinical problem. This study aims at assessing the relation between the activity level of an ectopic focus and the complexity of the ...

2009