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The superconducting magnet system of the Divertor Tokamak Test (DTT) facility, composed of 18 toroidal field (TF) coils, 6 poloidal field coils and a central solenoid, has been designed and many procurements have been launched. Some manufacturing aspects a ...
Recently, adaptive non-shivering thermogenesis has attracted considerable attention because it can elevate energy expenditure and help treat obesity. Despite the numerous reports related to UCP1-driven thermogenesis, little is known regarding UCP1-independ ...
The physiological contribution of glucose in thermoregulation is not completely established nor whether this control may involve a regulation of the melanocortin pathway. Here, we assessed thermoregulation and leptin sensitivity of hypothalamic arcuate neu ...
Current thermal comfort models used in practice do not consider physiological and psychological differences of people. With this respect, human thermo-physiology models (HTPM) are useful tools to assess human thermal comfort at local and overall levels of ...
Sunlight, temperature, and microbial grazing are among the environmental factors promoting the inactivation of viral pathogens in surface waters. Globally, these factors vary across time and space. The persistence of viral pathogens, and ultimately their e ...
Human thermo-physiology models (HTPM) are useful tools to assess dynamic and non-uniform human thermal states. However, they are developed based on the physiological data of an average person. In this paper, we present a detailed evaluation of two sophisti ...
Brain energy consumption is high and a very tightly regulated energy metabolism ensures correct performance. Neurons, the cells responsible for transmitting information via synapses, interact very closely with star shaped glial cells called astrocytes. Ast ...
Maintaining homeostasis in higher organisms involves a complex interplay of multiple ubiquitous and organ-specific molecular mechanisms that can be characterized using functional genomics technologies such as transcriptomics, proteomics, and metabonomics a ...
For type 1 Diabetes, insulin injection therapy is the most used treatment today, and insulin pumps are surely the most accurate therapeutic strategy. The insulin use temperature has to not exceed 37°C to prevent unwanted degradation and loss of function. T ...
Redox and energy balance plays a key role in determining microbial fitness. Efforts to redirect bacterial metabolism often involve overexpression and deletion of genes surrounding key central metabolites, such as pyruvate and acetyl-coA. In the case of met ...