Publications associées à Coincidence detection in neurobiology

Somatostatin enhances visual processing and perception by suppressing excitatory inputs to parvalbumin-positive interneurons in V1

Carl Petersen, Graham Knott, Catherine Maclachlan, Seung-Hee Lee

Somatostatin (SST) is a neuropeptide expressed in a major subtype of GABAergic interneurons in the cortex. Despite abundant expression of SST and its receptors, their modulatory function in cortical processing remains unclear. Here, we found that SST appli ...

2020

Modeling and Analysis of a Direct Time-of-Flight Sensor Architecture for LiDAR Applications

Edoardo Charbon, Chunmin Zhang, Preethi Padmanabhan

Direct time-of-flight (DTOF) is a prominent depth sensing method in light detection and ranging (LiDAR) applications. Single-photon avalanche diode (SPAD) arrays integrated in DTOF sensors have demonstrated excellent ranging and 3D imaging capabilities, ma ...

2019

Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals

Ursula Röthlisberger, Siri Camee van Keulen, Daniele Narzi, Paolo Carloni

Author summary Adenylyl cyclases (ACs) are enzymes that can translate extracellular signals into the intracellular molecule cAMP, which is thus a 2nd messenger of extracellular events. The brain expresses nine membrane-bound AC variants, and AC5 is the dom ...

PUBLIC LIBRARY SCIENCE2019

Cleaning strategy for carbon-based electrodes: Long-term propofol monitoring in human serum

Giovanni De Micheli, Giovanni Boero, Francesca Stradolini, Irene Taurino, Tugba Kilic

In this work, we present a novel electrochemical cleaning procedure for long-term electrochemical monitoring of propofol by using boron-doped diamond (BDD) and pencil graphite electrode (PGE). Propofol is an anesthetic that is widely used for long-lasting ...

2018

Specific synaptic input strengths determine the computational properties of excitation-inhibition integration in a sound localization circuit

Ralf Schneggenburger, Friedemann Zenke, Enida Gjoni, Brice Antoine Alexandre Bouhours

The lateral superior olive (LSO) is a binaural nucleus in the auditory brainstem in which excitation from the ipsilateral ear is integrated with inhibition from the contralateral ear. It is unknown whether the strength of the unitary inhibitory and excitat ...

WILEY2018

Timed Synaptic Inhibition Shapes NMDA Spikes, Influencing Local Dendritic Processing and Global I/O Properties of Cortical Neurons

Henry Markram, Eilif Benjamin Muller, Idan Segev, Giuseppe Chindemi, Michael Doron

The NMDA spike is a long-lasting nonlinear phenomenon initiated locally in the dendritic branches of a variety of cortical neurons. It plays a key role in synaptic plasticity and in single-neuron computations. Combining dynamic system theory and computatio ...

2017

Neuromodulated-Spike-Timing-Dependent Pasticity, and Theory of Three-Factor Learning Rules

Wulfram Gerstner, Nicolas Frémaux

Classical Hebbian learning puts the emphasis on joint pre- and postsynaptic activity, but neglects the potential role of neuromodulators. Since neuromodulators convey information about novelty or reward, the influence of neuromodulators on synaptic plastic ...

Frontiers Research Foundation2016

Network-timing-dependent plasticity

Henry Markram, Eilif Benjamin Muller, Daniel Keller, Vincent Delattre

Bursts of activity in networks of neurons are thought to convey salient information and drive synaptic plasticity. Here we report that network bursts also exert a profound effect on Spike-Timing-Dependent Plasticity (STDP). In acute slices of juvenile rat ...

2015

In Vivo Measurement of Cell-Type-Specific Synaptic Connectivity and Synaptic Transmission in Layer 2/3 Mouse Barrel Cortex

Carl Petersen, Aurélie Pala

Intracellular recordings of membrane potential in vitro have defined fundamental properties of synaptic communication. Much less is known about the properties of synaptic connectivity and synaptic transmission in vivo. Here, we combined single-cell opto-ge ...

Cell Press2015

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Coincidence detection in neurobiology

Somatostatin enhances visual processing and perception by suppressing excitatory inputs to parvalbumin-positive interneurons in V1

Modeling and Analysis of a Direct Time-of-Flight Sensor Architecture for LiDAR Applications

Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals

Cleaning strategy for carbon-based electrodes: Long-term propofol monitoring in human serum

Specific synaptic input strengths determine the computational properties of excitation-inhibition integration in a sound localization circuit

Timed Synaptic Inhibition Shapes NMDA Spikes, Influencing Local Dendritic Processing and Global I/O Properties of Cortical Neurons

Neuromodulated-Spike-Timing-Dependent Pasticity, and Theory of Three-Factor Learning Rules

Network-timing-dependent plasticity

In Vivo Measurement of Cell-Type-Specific Synaptic Connectivity and Synaptic Transmission in Layer 2/3 Mouse Barrel Cortex

Models of Reward-Modulated Spike-Timing-Dependent Plasticity

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Chattez avec Graph Search

Somatostatin enhances visual processing and perception by suppressing excitatory inputs to parvalbumin-positive interneurons in V1

Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals

Cleaning strategy for carbon-based electrodes: Long-term propofol monitoring in human serum

Neuromodulated-Spike-Timing-Dependent Pasticity, and Theory of Three-Factor Learning Rules

Models of Reward-Modulated Spike-Timing-Dependent Plasticity

Network-timing-dependent plasticity

Specific synaptic input strengths determine the computational properties of excitation-inhibition integration in a sound localization circuit

Timed Synaptic Inhibition Shapes NMDA Spikes, Influencing Local Dendritic Processing and Global I/O Properties of Cortical Neurons

In Vivo Measurement of Cell-Type-Specific Synaptic Connectivity and Synaptic Transmission in Layer 2/3 Mouse Barrel Cortex