Publications associées à Iobenguane

Roadmap toward the 10 ps time-of-flight PET challenge

Edoardo Charbon, Mathieu Benoit, Christian Morel, Joao Varela

Since the seventies, positron emission tomography (PET) has become an invaluable medical molecular imaging modality with an unprecedented sensitivity at the picomolar level, especially for cancer diagnosis and the monitoring of its response to therapy. Mor ...

IOP PUBLISHING LTD2020

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer

Kai Johnsson, Jairo Alexander Lozano Moreno, Yann Mathieu Pierson

Genetic regulators and environmental stimuli modulate T cell activation in autoimmunity and cancer. The enzyme co-factor tetrahydrobiopterin (BH4) is involved in the production of monoamine neurotransmitters, the generation of nitric oxide, and pain(1,2). ...

NATURE PUBLISHING GROUP2018

Enzyme and Acid Deconjugation of Plasma Sulfated Metanephrines

Sandrine Gerber

Background: Total (i.e. free + sulfated) metanephrines in plasma is a biomarker for the diagnosis of pheochromocytoma/paraganglioma. Sulfated metanephrines must be completely deconjugated by perchloric acid hydrolysis or sulfatase treatment prior to analyt ...

Elsevier2014

In vivo MRI assessment of a novel GdIII-based contrast agent designed for high magnetic field applications

André Merbach, Lothar Helm, Eva Jakab Toth, Joao Bruno Livramento Fig.

Gd3L is a trinuclear Gd3R complex of intermediate size, designed for contrast agent applications in high field magnetic resonance imaging (H12L is based on a trimethylbenzene core bearing three methylene-diethylenetriamine-N,N,N00,N00-tetraacetate moieties ...

2008

First in vivo MRI assessment of a self-assembled metallostar compound endowed with a remarkable high field relaxivity

André Merbach, Lothar Helm, Eva Jakab Toth, Joao Bruno Livramento Fig.

{Fe[Gd2bpy(DTTA)2(H2O)4]3}4- is a self-assembled, metallostar-structured potential MRI contrast agent, with six efficiently relaxing Gd3+ centers confined into a small mol. space. Its proton relaxivity is particularly remarkable at very high magnetic field ...

2006