Concept

Environmental toxicology

Publications associées (33)

The use of fish-derived cell lines for investigation of environmental contaminants: an update following OECD’s fish toxicity testing framework No. 171.

Protocols for evaluating chemical toxicity at the cellular level using fish cell lines are described in this unit. Routine methodologies for growing salmonid cell lines, and using them in aquatic toxicology studies that support the mandate of the Organizat ...

wileyonlinelibrary.com2013

Effect-based tools for monitoring and predicting the ecotoxicological effects of chemicals in the environment

Ecotoxicology faces the challenge of assessing and predicting the effects of an increasing number of chemical stressors on aquatic species and ecosystems. Herein we review currently applied tools in ecological risk assessment, combining information on expo ...

2012

Comparative evaluation of particle properties, formation of reactive oxygen species and genotoxic potential of tungsten carbide based nanoparticles in vitro

Kristin Schirmer

Tungsten carbide (WC) and cobalt (Co) are constituents of hard metals and are used for the production of extremely hard tools. Previous studies have identified greater cytotoxic potential of WC-based nanopartides if particles contained Co. The aim of this ...

Elsevier Science Bv2012

Postpolymerization modification of poly(pentafluorophenyl methacrylate): Synthesis of a diverse water-soluble polymer library

Harm-Anton Klok, Matthew Gibson

This article explores the feasibility of poly(pentafluorophenyl methacrylate) (PPFMA) prepared by reversible addition fragmentation chain transfer (RAFT) polymerization as a platform for the preparation of diverse libraries of functional polymers via postp ...

2009

USEtox-the UNEP-SETAC toxicity model: recommended characterisation factors for human toxicity and freshwater ecotoxicity in life cycle impact assessment

Jérôme Payet

Background, aim and scope In 2005, a comprehensive comparison of life cycle impact assessment toxicity characterisation models was initiated by the United Nations Environment Program (UNEP)-Society for Environmental Toxicology and Chemistry (SETAC) Life Cy ...

2008

Risk and regulatory hazard-based toxicological effect indicators in life-cycle assessment (LCA)

In life-cycle assessment (LCA), it is desirable to compare quantities of chemicals released into the environment in terms of the risk and consequences of toxicological effects. Many current methods rely directly on adaptations of regulatory-orientated appr ...

Taylor & Francis2006

Characterization of a microfluidic dispensing system for localised stimulation of cellular networks

Nico de Rooij

We present a 3-D microfluidic device designed for localized drug delivery to cellular networks. The device features a flow cell comprising a main channel for nutrient delivery as well as multiple channels for drug delivery. This device is one key component ...

2006

Proposal to improve vertebrate cell cultures to establish them as substitutes for the regulatory testing of chemicals and effluents using fish

Kristin Schirmer

Cultures of vertebrate cells are widely applied in mechanistic studies in human toxicology as well as in toxicity identification in ecotoxicology. As in vitro models, they display many advantages over whole animal experimentation, pertaining to such charac ...

2006

Synchrotron microradiography study on acute lung injury of mouse caused by PM2.5 aerosols

Yiming Li, Giorgio Margaritondo

In order to investigate FeSO4, ZnSO4 (the two of main metal compositions of Shanghai PM2.5 (particle matter with those aerodynamical diameter

Elsevier2006

Multimedia fate and human intake modeling: Spatial versus nonspatial insights for chemical emissions in Western Europe

Multimedia fate and multipathway human,exposure models are widely adopted in assessments of toxicological risks of chemical emissions at the regional scale. This paper addresses the question of how much spatial detail is necessary in such models when estim ...

2005

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