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National Center for Biotechnology Information

Publications associées (22)

Fifteen years SIB Swiss Institute of Bioinformatics: life science databases, tools and support

Jacques Rougemont, Philipp Bucher, Mauro Delorenzi, Heinz Stockinger, Ioannis Xenarios, Olivier Michielin, Amos Bairoch

The SIB Swiss Institute of Bioinformatics (www.isb-sib.ch) was created in 1998 as an institution to foster excellence in bioinformatics. It is renowned worldwide for its databases and software tools, such as UniProtKB/Swiss-Prot, PROSITE, SWISS-MODEL, STRI ...

Oxford University Press2014

Culture and Characterization of Human and Porcine Urothelial Progenitor Cells

Hans Mattias Larsson

An estimated 400 million people worldwide suffer from bladder diseases. However, little is known at the cellular level as to what causes or initiates many of these diseases. Therefore, this thesis has focused on understanding one cell type within the bladd ...

EPFL2012

A Rate-based Prefiltering Approach to BLAST Acceleration

Dionysios Pnevmatikatos, Sotiria Fytraki

DNA sequence comparison and database search have evolved in the last years as a field of strong competition between several reconfigurable hardware computing groups. In this paper we present a BLAST preprocessor that efficiently marks the parts of the data ...

2008

Vertebrate conserved non coding DNA regions have a high persistence length and a short persistence time

Philipp Bucher

ABSTRACT: BACKGROUND: The comparison of complete genomes has revealed surprisingly large numbers of conserved non-protein-coding (CNC) DNA regions. However, the biological function of CNC remains elusive. CNC differ in two aspects from conserved protein-co ...

2007

Recent improvements to the PROSITE database

Philipp Bucher, Amos Bairoch

The PROSITE database consists of a large collection of biologically meaningful signatures that are described as patterns or profiles. Each signature is linked to documentation that provides useful biological information on the protein family, domain or fun ...

2004

CleanEx: a database of heterogeneous gene expression data based on a consistent gene nomenclature

Philipp Bucher

The main goal of CleanEx is to provide access to public gene expression data via unique gene names. A second objective is to represent heterogeneous expression data produced by different technologies in a way that facilitates joint analysis and cross-data ...

2004

PROSITE: a documented database using patterns and profiles as motif descriptors

Philipp Bucher, Amos Bairoch

Among the various databases dedicated to the identification of protein families and domains, PROSITE is the first one created and has continuously evolved since. PROSITE currently consists of a large collection of biologically meaningful motifs that are de ...

2002

The Eukaryotic Promoter Database, EPD: new entry types and links to gene expression data

Philipp Bucher, Rouayda Cavin Perier

The Eukaryotic Promoter Database (EPD) is an annotated, non-redundant collection of eukaryotic Pol II promoters, for which the transcription start site has been determined experimentally. Access to promoter sequences is provided by pointers to positions in ...

2002

The eukaryotic promoter database (EPD)

Philipp Bucher, Rouayda Cavin Perier

The Eukaryotic Promoter Database (EPD) is an annotated non-redundant collection of eukaryotic POL II promoters for which the transcription start site has been determined experimentally. Access to promoter sequences is provided by pointers to positions in n ...

2000

The Eukaryotic Promoter Database (EPD): recent developments

Philipp Bucher, Rouayda Cavin Perier

The Eukaryotic Promoter Database (EPD) is an annotated non-redundant collection of eukaryotic POL II promoters, for which the transcription start site has been determined experimentally. Access to promoter sequences is provided by pointers to positions in ...

1999

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