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Computational approaches are breaking new ground in understanding how embryos form. Here, we discuss recent studies that couple precise measurements in the embryo with appropriately matched modeling and computational methods to investigate classic embryoni ...
This article is concerned with the evolution of haploid organisms that reproduce asexually. In a seminal piece of work, Eigen and coauthors proposed the quasispecies model in an attempt to understand such an evolutionary process. Their work has impacted an ...
The experimental determination of transcriptional regulatory networks in the laboratory remains difficult and time-consuming, while computational methods to infer these networks provide only modest accuracy. The latter can be attributed partly to the limit ...
In this paper, a mixed numerical-experimental identification procedure for characterising the storage and loss properties in sandwich structures with a relatively stiff core is developed. At the computational level, the proposed method is based upon an ori ...
In the past few decades the scientific community has been recognizing the paramount role of the cell microenvironment in determining cell behavior. In parallel, the study of human stem cells for their potential therapeutic applications has been progressing ...
There are many works in colour that assume illumination change can be modelled by multiplying sensor responses by individual scaling factors. The early research in this area are sometimes grouped under the heading von Kries adaptation: the scaling factors ...
The complexity of stem cell niches poses a tremendous challenge to understanding mechanisms of extrinsic regulation of stem cell fate. In order to better understand niche signaling and its effect on stem cell fate choices, in vitro systems are being engine ...
The diversity of modeling approaches in computational neuroscience makes model sharing, retrieval, reuse and reproducibility difficult and even sometimes impossible. To address this problem, standardized languages have been developed by and for the communi ...
Our interest is to characterize the spline-like integer-shift-invariant bases capable of reproducing exponential polynomial curves. We prove that any compact-support function that reproduces a subspace of the exponential polynomials can be expressed as the ...
The regeneration of large bone defects caused by trauma or disease remains a significant clinical problem. Although osteoinductive growth factors such as bone morphogenetic proteins have entered clinics, transplantation of autologous bone remains the gold ...