Publications associées à Plaque neurale

Droplet extraction module for the analysis of segmented flow generated by a neural probe

Philippe Renaud, Arnaud Bertsch, Guillaume Cédric Yves Petitpierre, Colin Darbellay

We recently developed a neural probe allowing to capture at high temporal resolution nano-volume droplets of interstitial fluid from the brain organized in a segmented flow. In order to enable the analysis of these small volume and low concentration drople ...

2016

Haplosufficiency of PAX3 for melanoma development in Tyr: NRASQ61K; Cdkn2a-/- mice allows identification and sorting of melanoma cells using a Pax3GFP reporter allele

Friedrich Beermann

The role of the Pax3 gene in embryonic development of pigment cells is well characterized. By contrast, the function of Pax3 in melanoma development is controversial. Indeed, data obtained from cultured cells suggest that PAX3 may contribute to melanomagen ...

Lippincott Williams & Wilkins2016

Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation

Bernard Schneider

Microphthalmia-associated transcription factor (MITF) is a master regulator of pigmented cell survival and differentiation with direct transcriptional links to cell cycle, apoptosis and pigmentation. In mouse, Mitf is expressed early and uniformly in optic ...

Oxford University Press2014

Combined function of HoxA and HoxB clusters in neural crest cells

Denis Duboule, Maxence Vieux-Rochas

The evolution of chordates was accompanied by critical anatomical innovations in craniofacial development, along with the emergence of neural crest cells. The potential of these cells to implement a craniofacial program in part depends upon the (non-)expre ...

Academic Press Inc Elsevier Science2013

Undirected compensatory plasticity contributes to neuronal dysfunction after severe spinal cord injury

Grégoire Courtine, Quentin Barraud, Pavel Musienko, Rubia van den Brand, Lucia Florinda Friedli Wittler, Janine Beauparlant

Severe spinal cord injury in humans leads to a progressive neuronal dysfunction in the chronic stage of the injury. This dysfunction is characterized by premature exhaustion of muscle activity during assisted locomotion, which is associated with the emerge ...

Oxford University Press2013

BMP signaling specifies the development of a large and fast CNS synapse

Graham Knott, Ralf Schneggenburger, Enida Gjoni, Elin Kristina Kronander, Le Xiao

excitatory synapses with multiple active zones ensure reliable and fast information transfer at specific points in neuronal circuits. However, the mechanisms that determine synapse size in CNS circuits are largely unknown. Here we use the calyx of Held syn ...

Nature Publishing Group2013

Constitutive gray hair in Mice induced by Melanocyte-specific deletion of c-Myc

Friedrich Beermann, Karine Schouwey, Marzia Armaro

c-Myc is involved in the control of diverse cellular processes and implicated in the maintenance of different tissues including the neural crest. Here we report that c-Myc is particularly important for pigment cell development and homeostasis. Targeting c- ...

2012

Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma

Yann Barrandon, Friedrich Beermann, Stéphanie Claudinot, Lukas Sommer

Giant congenital naevi are pigmented childhood lesions that frequently lead to melanoma, the most aggressive skin cancer. The mechanisms underlying this malignancy are largely unknown, and there are no effective therapies. Here we describe a mouse model fo ...

Nature Publishing Group2012

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Plaque neurale

In vitro modeling of complex microenvironmental regulation of stem cells

Droplet extraction module for the analysis of segmented flow generated by a neural probe

Haplosufficiency of PAX3 for melanoma development in Tyr: NRASQ61K; Cdkn2a-/- mice allows identification and sorting of melanoma cells using a Pax3GFP reporter allele

Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation

Combined function of HoxA and HoxB clusters in neural crest cells

Undirected compensatory plasticity contributes to neuronal dysfunction after severe spinal cord injury

BMP signaling specifies the development of a large and fast CNS synapse

Regulatory Switches Underlie Hoxd Gene Activation in Tetrapod Limbs

Constitutive gray hair in Mice induced by Melanocyte-specific deletion of c-Myc

Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma

Graph Chatbot

Chattez avec Graph Search

Haplosufficiency of PAX3 for melanoma development in Tyr: NRASQ61K; Cdkn2a-/- mice allows identification and sorting of melanoma cells using a Pax3GFP reporter allele

Constitutive gray hair in Mice induced by Melanocyte-specific deletion of c-Myc

Regulatory Switches Underlie Hoxd Gene Activation in Tetrapod Limbs

Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma

In vitro modeling of complex microenvironmental regulation of stem cells

Combined function of HoxA and HoxB clusters in neural crest cells

Droplet extraction module for the analysis of segmented flow generated by a neural probe

Undirected compensatory plasticity contributes to neuronal dysfunction after severe spinal cord injury

Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation

BMP signaling specifies the development of a large and fast CNS synapse